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Vesnarinone AHFS /Drugs.com International Drug Names Routes of administration By mouth ATC code Legal status
In general: ℞ (Prescription only)
6-[4-(3,4-Dimethoxybenzoyl)piperazin-1-yl]-3,4-dihydro-1H-quinolin-2-one
CAS Number PubChem CID ChemSpider UNII ChEMBL CompTox Dashboard (EPA ) Formula C 22 H 25 N 3 O 4 Molar mass 395.459 g·mol−1 3D model (JSmol )
COC1=C(C=C(C=C1)C(=O)N2CCN(CC2)C3=CC4=C(C=C3)NC(=O)CC4)OC
InChI=1S/C22H25N3O4/c1-28-19-7-3-16(14-20(19)29-2)22(27)25-11-9-24(10-12-25)17-5-6-18-15(13-17)4-8-21(26)23-18/h3,5-7,13-14H,4,8-12H2,1-2H3,(H,23,26)
N Key:ZVNYJIZDIRKMBF-UHFFFAOYSA-N
N
N Y (what is this?)
Vesnarinone (INN ) is a cardiotonic agent.
A mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic activity. Vesnarinone improves ventricular performance most in patients with the worst degree of heart failure .
External links [ ]
Cardiac stimulants excluding cardiac glycosides (C01C )
Adrenergic anddopaminergic agents
Phosphodiesterase inhibitors (PDE3I )Other cardiac stimulants
# WHO-EM
‡ Withdrawn from market
Clinical trials :
† Phase III
§ Never to phase III
Piperazines
Simple piperazines(no additional rings) Phenylpiperazines
2C-B-PP
3,4-CFP
Acaprazine
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Batoprazine
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BRL-15,572
Ciprofloxacin
CSP-2503
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DCPP
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EGIS-12,233
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Ensaculin
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S-14,506
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SB-258,585
SB-271,046
SB-357,134
SB-399,885
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Vortioxetine
WAY-100,135
WAY-100,635
Benzylpiperazines Diphenylalkylpiperazines (benzhydrylalkylpiperazines) Pyrimidinylpiperazines Pyridinylpiperazines Benzo(iso)thiazolyl piperazines Tricyclics (piperazine attached via side chain) Others/Uncategorized
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Drugs not assigned an ATC code N-benzoylpiperazines Inotropic agents PDE3 inhibitors Catechol ethers Phenylpiperazines 2-Quinolones Cardiovascular system drug stubs Hidden categories:
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