From Wikipedia, the free encyclopedia
This article
relies largely or entirely on a single source .
Relevant discussion may be found on the talk page . Please help by introducing citations to additional sources .Find sources: – · · · scholar · JSTOR (November 2014 )
Proxyphylline
Names
IUPAC name
7-(2-Hydroxypropyl)-1,3-dimethylpurine-2,6-dione
Identifiers
CAS Number
3D model (JSmol )
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard
100.009.117
EC Number
KEGG
UNII
InChI=1S/C10H14N4O3/c1-6(15)4-14-5-11-8-7(14)9(16)13(3)10(17)12(8)2/h5-6,15H,4H2,1-3H3
N Key: KYHQZNGJUGFTGR-UHFFFAOYSA-N
N
CC(CN1C=NC2=C1C(=O)N(C(=O)N2C)C)O
Properties
Chemical formula
C10 H14 N4 O3
Molar mass
238.24316
Pharmacology
ATC code
R03DA03 (WHO )
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N (what is Y N ?)
Infobox references
Chemical compound
Proxyphylline is a xanthine derivative that acts as a cardiac stimulant , vasodilator and bronchodilator .[1]
References [ ]
Drugs for
obstructive airway diseases :
asthma /
COPD (
R03 )
Adrenergics , inhalants
Short-acting β2 agonists Long-acting β2 agonists Ultra-long-acting β2 agonists Other
Glucocorticoids Anticholinergics /muscarinic antagonist Mast cell stabilizers Xanthines Eicosanoid inhibition
Leukotriene antagonists Arachidonate 5-lipoxygenase inhibitors Thromboxane receptor antagonists Non-xanthine PDE4 inhibitors
Others/unknown Combination products
# WHO-EM
‡ Withdrawn from market
Clinical trials :
† Phase III
§ Never to phase III
Receptor (ligands )
P0 (adenine )P1 (adenosine )P2 (nucleotide )
P2X (ATP )
Agonists:
Adenosine
ADP
AMP
Ap4A
ATP
CTP
GTP
Ivermectin
UTP
Zinc
P2Y
Transporter (blockers )
CNTs
Adenosine
Estradiol
Phloridzin
Progesterone
ENTs PMAT
Enzyme (inhibitors )
Others
Others: Chrysophanol (rhubarb )
See also: Receptor/signaling modulators
Categories :
Adenosine receptor antagonists Phosphodiesterase inhibitors Xanthines Respiratory system drug stubs Alkaloid stubs Hidden categories:
Articles needing additional references from November 2014 All articles needing additional references Articles without InChI source Chembox CAS registry number linked Articles with changed EBI identifier Articles with changed ChemSpider identifier ECHA InfoCard ID from Wikidata Articles with changed KEGG identifier Articles with changed FDA identifier Articles with changed InChI identifier Pages using collapsible list with both background and text-align in titlestyle Articles containing unverified chemical infoboxes Chembox image size set Articles with short description Short description matches Wikidata All stub articles