Manidipine
![]() | |
Clinical data | |
---|---|
Trade names | Manyper, etc. |
AHFS/Drugs.com | International Drug Names |
Routes of administration | Oral |
ATC code |
|
Legal status | |
Legal status |
|
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
CompTox Dashboard (EPA) | |
Chemical and physical data | |
Formula | C35H38N4O6 |
Molar mass | 610.711 g·mol−1 |
3D model (JSmol) | |
SMILES
| |
InChI
|
Manidipine is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive.[1][2][3][4][5]
It was patented in 1982 and approved for medical use in 1990.[6]
References[]
- ^ Cheer SM, McClellan K (2001). "Manidipine: a review of its use in hypertension". Drugs. 61 (12): 1777–99. doi:10.2165/00003495-200161120-00010. PMID 11693466. Archived from the original on 2013-01-17. Retrieved 2009-06-20.
- ^ McKeage K, Scott LJ (2004). "Manidipine: a review of its use in the management of hypertension". Drugs. 64 (17): 1923–40. doi:10.2165/00003495-200464170-00011. PMID 15329044. Archived from the original on 2013-01-16. Retrieved 2009-06-20.
- ^ Roca-Cusachs A, Triposkiadis F (2005). "Antihypertensive effect of manidipine". Drugs. 65 Suppl 2: 11–9. doi:10.2165/00003495-200565002-00003. PMID 16398058. S2CID 25854593. Archived from the original on 2013-01-16. Retrieved 2009-06-20.
- ^ Otero ML (2007). "Manidipine-delapril combination in the management of hypertension". Vascular Health and Risk Management. 3 (3): 255–63. PMC 2293964. PMID 17703633.
- ^ Mizuno K, Haga H, Takahashi M, Fukuchi S (August 1992). "Evaluation of manidipine hydrochloride, a new calcium antagonist, in the treatment of hypertensive patients with renal disorders". Current Therapeutic Research. 52 (2): 248–253. doi:10.1016/S0011-393X(05)80475-8.
- ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 465. ISBN 9783527607495.
Categories:
- Calcium channel blockers
- Cyclizines
- Dihydropyridines
- Nitrobenzenes
- Carboxylate esters
- Cardiovascular system drug stubs