Sodium channel opener
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A sodium channel opener is a type of drug which facilitates ion transmission through sodium channels.
Examples include toxins, such as aconitine, veratridine, batrachotoxin, robustoxin, palytoxin and ciguatoxins and insecticides (DDT and pyrethroids), which activate voltage-gated sodium channels (VGSCs), and (AP301), which activates the epithelial sodium channel (ENaC).[1]
See also[]
- Sodium channel blocker
References[]
- ^ Shabbir W, Tzotzos S, Bedak M, Aufy M, Willam A, Kraihammer M, Holzner A, Czikora I, Scherbaum-Hazemi P, Fischer H, Pietschmann H, Fischer B, Lucas R, Lemmens-Gruber R (2015). "Glycosylation-dependent activation of epithelial sodium channel by solnatide". Biochem. Pharmacol. 98 (4): 740–53. doi:10.1016/j.bcp.2015.08.003. PMID 26254591.
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See also: Receptor/signaling modulators • Transient receptor potential channel modulators |
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