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Choline theophyllinate Trade names Choledyl, Theocolin Other names Oxtriphylline AHFS /Drugs.com International Drug Names ATC code Excretion mainly via kidneys show (2-Hydroxyethyl)trimethylazanium; 1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H -purin-7-ide
CAS Number PubChem CID DrugBank ChemSpider UNII KEGG ChEMBL CompTox Dashboard (EPA ) ECHA InfoCard 100.022.545 Formula C 12 H 21 N 5 O 3 Molar mass −1 3D model (JSmol ) show Cn1c(c-2ncnc2n(c1=O)C)[O-].C[N+](C)(C)CCO
show InChI=1S/C7H8N4O2.C5H14NO/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;1-6(2,3)4-5-7/h3,12H,1-2H3;7H,4-5H2,1-3H3/q;+1/p-1
Key:SOELXOBIIIBLRJ-UHFFFAOYSA-M
Choline theophyllinate (INN ), also known as oxtriphylline , is a cough medicine derived from xanthine that acts as a bronchodilator to open up airways in the lung. Chemically, it is a salt of choline and theophylline . It classifies as an expectorant .[citation needed The drug is available under the brand names Choledyl and Choledyl SA , among others.[1]
References [ ] show Drugs for
obstructive airway diseases :
asthma /
COPD (
R03 )
Adrenergics , inhalants
Short-acting β2 agonists Long-acting β2 agonists Ultra-long-acting β2 agonists Other
Glucocorticoids Anticholinergics /muscarinic antagonist Mast cell stabilizers Xanthines Eicosanoid inhibition
Leukotriene antagonists Arachidonate 5-lipoxygenase inhibitors Thromboxane receptor antagonists Non-xanthine PDE4 inhibitors
Others/unknown Combination products
# WHO-EM ‡ Withdrawn from marketClinical trials :
† Phase III § Never to phase III
show Receptor (ligands )
P0 (adenine )P1 adenosine )P2 nucleotide )
P2X ATP
Agonists: Adenosine ADP AMP Ap4A ATP CTP GTP Ivermectin UTP Zinc P2Y
Transporter (blockers )
CNTs
Adenosine Estradiol Phloridzin Progesterone ENTs PMAT
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Others
Precursors: Adenine Adenosine AMP ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP ITP Ribose Uracil Uridine UMP UDP UTP Others: Chrysophanol (rhubarb ) See also: Receptor/signaling modulators
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