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AB-FUBICA Legal status
CA Schedule II DE NpSG (Industrial and scientific use only) UK :Class B
N -[(1S )-1-(Aminocarbonyl)-2-methylpropyl]-1-[(4-fluorophenyl)methyl]-1H -indole-3-carboxamide
CAS Number ChemSpider UNII Formula C 21 H 22 F N 3 O 2 Molar mass −1 3D model (JSmol )
O=C(N[C@H](C(N)=O)C(C)C)C1=CN(CC2=CC=C(F)C=C2)C3=CC=CC=C31
InChI=1S/C21H22FN3O2/c1-13(2)19(20(23)26)24-21(27)17-12-25(18-6-4-3-5-16(17)18)11-14-7-9-15(22)10-8-14/h3-10,12-13,19H,11H2,1-2H3,(H2,23,26)(H,24,27)/t19-/m0/s1
Key:KTVPQJSKKGZIEA-IBGZPJMESA-N
AB-FUBICA is a drug that acts as a potent agonist for the cannabinoid receptors , with EC50 values of 21 nM at CB1 and 15 nM at CB2 .[1] [2]
See also [ ] References [ ]
^ Banister SD, Moir M, Stuart J, Kevin RC, Wood KE, Longworth M, et al. (September 2015). "Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, and 5F-ADBICA". ACS Chemical Neuroscience . 6 (9): 1546–59. doi :10.1021/acschemneuro.5b00112 . PMID 26134475 . ^ Qian Z, Hua Z, Liu C, Jia W (November 2015). "Four types of cannabimimetic indazole and indole derivatives, ADB-BINACA, AB-FUBICA, ADB-FUBICA, and AB-BICA, identified as new psychoactive substances" . Forensic Toxicology . 34 : 133–143. doi :10.1007/s11419-015-0297-2 . PMC 4705129 PMID 26793280 .
Cannabinoids
Phytocannabinoids
Cannabichromenes Cannabicyclols Cannabidiols Cannabielsoins Cannabigerols Cannabinols and cannabinodiols Cannabitriols Delta-8-tetrahydrocannabinols Delta-9-tetrahydrocannabinols
Delta-9-THC (THC)
THCH THCP
THCV
Miscellaneous cannabinoids Active metabolites
Endocannabinoids
Arachidonoyl ethanolamide (AEA; anandamide) 2-Arachidonoylglycerol (2-AG) 2-Arachidonyl glyceryl ether (2-AGE; noladin ether) 2-Oleoylglycerol (2-OG) N-Arachidonoyl dopamine (NADA) N-Arachidonylglycine (NAGly) N-Arachidonoyl serotonin (AA-5-HT) Docosatetraenoylethanolamide (DEA) Lysophosphatidylinositol (LPI) Oleamide Oleoylethanolamide (OEA) Palmitoylethanolamide (PEA) RVD-Hpα Stearoylethanolamide (SEA) O-Arachidonoyl ethanolamine (O-AEA; virodhamine) Synthetic
Classical cannabinoids Non-classical Adamantoylindoles Benzimidazoles Benzoylindoles Cyclohexylphenols Eicosanoids Hydrocarbons Indazole carboxamides Indazole-3- Indole-3-carboxamides Indole-3-carboxylates Naphthoylindazoles Naphthoylindoles Naphthoylpyrroles Naphthylmethylindenes Naphthylmethylindoles Phenylacetylindoles Pyrazolecarboxamides Pyrrolobenzoxazines Quinolinyl esters Tetramethylcyclo- Tetramethylcyclo-
A-796,260 A-834,735 FUB-144 UR-144 XLR-11 XLR-12 Tetramethylcyclo- Others
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See also: Cannabinoid receptor modulators (cannabinoids by pharmacology)List of: AM cannabinoids JWH cannabinoids Designer drugs § Synthetic cannabimimetics
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