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MK-4409 ATC code Legal status
US : Investigational New Drug
2-[5-[5-(5-Chloropyridin-2-yl)sulfanyl-2-(4-fluorophenyl)-1,3-oxazol-4-yl]pyridin-2-yl]propan-2-ol
CAS Number PubChem CID ChemSpider UNII ChEMBL Formula C 22 H 17 F N 3 O 2 S Molar mass 406.46 g·mol−1 3D model (JSmol )
c3nc(C(O)(C)C)ccc3-c1nc(-c4ccc(F)cc4)oc1Sc(nc2)ccc2Cl
InChI=1S/C22H17ClFN3O2S/c1-22(2,28)17-9-5-14(11-25-17)19-21(30-18-10-6-15(23)12-26-18)29-20(27-19)13-3-7-16(24)8-4-13/h3-12,28H,1-2H3
Key:DBZMCSVIITXLCC-UHFFFAOYSA-N
MK-4409 is an experimental drug which acts as a potent and selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH), with an IC50 of 11 nM, and both analgesic and antiinflammatory effects in animal studies. It was studied for the treatment of neuropathic pain and progressed to early stage human clinical trials by 2009.[1] [2]
See also [ ]
LY-2183240
URB-597
PF-3845
BIA 10-2474
References [ ]
External links [ ]
"MK 4409" . Adis Insight . Springer Nature Switzerland AG.
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