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α-Methylhistamine
Names
IUPAC name
1-(3H -Imidazol-4-yl)propan-2-amine
Systematic IUPAC name
1-(1
H -Imidazol-4-yl)propan-2-amine
[1]
Identifiers
3D model (JSmol )
ChEBI
ChEMBL
ChemSpider
IUPHAR/BPS
MeSH
Alpha-methylhistamine
InChI=1S/C6H11N3/c1-5(7)2-6-3-8-4-9-6/h3-5H,2,7H2,1H3,(H,8,9)
Y Key: XNQIOISZPFVUFG-UHFFFAOYSA-N
Y InChI=1/C6H11N3/c1-5(7)2-6-3-8-4-9-6/h3-5H,2,7H2,1H3,(H,8,9)
Key: XNQIOISZPFVUFG-UHFFFAOYAW
Properties
C 6 H 11 N 3
Molar mass
125.175 g·mol−1
log P
-0.346
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N (what is Y N ?)
Infobox references
Chemical compound
α-Methylhistamine is a histamine agonist selective for the receptor subtype H3 . It causes lowering of blood pressure and a decrease of heart rate in animal models.[2]
References [ ]
H1
Agonists Antagonists
Others: Atypical antipsychotics (e.g., aripiprazole , asenapine , brexpiprazole , brilaroxazine , clozapine , iloperidone , olanzapine , paliperidone , quetiapine , risperidone , ziprasidone , zotepine )
Phenylpiperazine antidepressants (e.g., hydroxynefazodone , nefazodone , trazodone , triazoledione )
Tetracyclic antidepressants (e.g., amoxapine , loxapine , maprotiline , mianserin , mirtazapine , oxaprotiline )
Tricyclic antidepressants (e.g., amitriptyline , butriptyline , clomipramine , desipramine , dosulepin (dothiepin) , doxepin , imipramine , iprindole , lofepramine , nortriptyline , protriptyline , trimipramine )
Typical antipsychotics (e.g., chlorpromazine , flupenthixol , fluphenazine , loxapine , perphenazine , prochlorperazine , thioridazine , thiothixene )
H2
H3
H4
See also: Receptor/signaling modulators • Monoamine metabolism modulators • Monoamine reuptake inhibitors
Categories :
Imidazoles Amines Histamine agonists Cardiovascular system drug stubs Hidden categories:
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