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Methimepip
Names
IUPAC name
4-(1H -imidazol-4-ylmethyl)-1-methylpiperidine
Identifiers
3D model (JSmol )
ChEMBL
ChemSpider
IUPHAR/BPS
MeSH
C500075
InChI=1S/C10H17N3/c1-13-4-2-9(3-5-13)6-10-7-11-8-12-10/h7-9H,2-6H2,1H3,(H,11,12)
N Key: KIAVPENCSGKVQP-UHFFFAOYSA-N
N InChI=1/C10H17N3/c1-13-4-2-9(3-5-13)6-10-7-11-8-12-10/h7-9H,2-6H2,1H3,(H,11,12)
Key: KIAVPENCSGKVQP-UHFFFAOYAQ
Properties
C10 H17 N3
Molar mass
179.262 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N (what is Y N ?)
Infobox references
Chemical compound
Methimepip is a histamine agonist which is highly selective for the H3 subtype. It is the N -methyl derivative of immepip .[1]
References [ ]
^ Kitbunnadaj R, Hashimoto T, Poli E, et al. (March 2005). "N -substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist". Journal of Medicinal Chemistry . 48 (6): 2100–7. doi :10.1021/jm049475h . PMID 15771452 .
H1
Agonists Antagonists
Others: Atypical antipsychotics (e.g., aripiprazole , asenapine , brexpiprazole , brilaroxazine , clozapine , iloperidone , olanzapine , paliperidone , quetiapine , risperidone , ziprasidone , zotepine )
Phenylpiperazine antidepressants (e.g., hydroxynefazodone , nefazodone , trazodone , triazoledione )
Tetracyclic antidepressants (e.g., amoxapine , loxapine , maprotiline , mianserin , mirtazapine , oxaprotiline )
Tricyclic antidepressants (e.g., amitriptyline , butriptyline , clomipramine , desipramine , dosulepin (dothiepin) , doxepin , imipramine , iprindole , lofepramine , nortriptyline , protriptyline , trimipramine )
Typical antipsychotics (e.g., chlorpromazine , flupenthixol , fluphenazine , loxapine , perphenazine , prochlorperazine , thioridazine , thiothixene )
H2
H3
H4
See also: Receptor/signaling modulators • Monoamine metabolism modulators • Monoamine reuptake inhibitors
Categories :
Imidazoles Histamine agonists Piperidines Pharmacology stubs Hidden categories:
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