4-Bromo-2,5-dimethoxy-1-benzylpiperazine (2C-B-BZP) is a psychoactive drug and research chemical of the piperazinechemical class which has been sold as a "designer drug".[1][2] It produces stimulant effects similar to those of benzylpiperazine (BZP).
2C-B-BZP contains a benzylpiperazine base as well as the ring-substitution pattern of the psychedelicphenethylamine2C-B. 2C-B-BZP is not a phenethylamine itself and does not produce psychedelic effects, as the binding groups are in the wrong position to activate the 5-HT2A receptor, while the phenylpiperazine homologue 2C-B-PP substitutes for DOM in DOM-trained rats with around 1/10th the potency of DOM, but does not substitute for TFMPP.[3]: 867–868
Effects[]
2C-B-BZP produces stimulant effects which last 3–6 hours. It is also said by several sources to increase the effects of other compounds when combined[citation needed]. Side effects include headaches and nausea, similar to those of other recreationally-used piperazine derivatives.
Legality[]
2C-B-BZP is unscheduled and uncontrolled in the United States, but possession and sale of 2C-B-BZP could possibly be prosecuted under the Federal Analog Act because of its structural similarities to benzylpiperazine. 2C-B-BZP is illegal to possess, use or sell in Japan where it used to be sold in local smartshops.
^Westphal F, Junge T, Girreser U, Stobbe S, Pérez SB (May 2009). "Structure elucidation of a new designer benzylpiperazine: 4-bromo-2,5-dimethoxybenzylpiperazine". Forensic Science International. 187 (1–3): 87–96. doi:10.1016/j.forsciint.2009.03.003. PMID19345524.
^Peters FT, Martinez-Ramirez JA (October 2010). "Analytical toxicology of emerging drugs of abuse". Therapeutic Drug Monitoring. 32 (5): 532–9. doi:10.1097/FTD.0b013e3181f33411. PMID20814349.
^Daniel Trachsel; David Lehmann & Christoph Enzensperger (2013). Phenethylamine: Von der Struktur zur Funktion. Nachtschatten Verlag AG. ISBN978-3-03788-700-4.