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CD302 Identifiers Aliases CD302 , BIMLEC, CLEC13A, DCL-1, DCL1, CD302 moleculeExternal IDs OMIM : 612246 MGI : 1913455 HomoloGene : 8919 GeneCards : CD302 Gene location (Human ) Chr. Chromosome 2 (human) [1] Band 2q24.2 Start 159,768,628 bp [1] End 159,798,255 bp [1]
Gene location (Mouse ) Chr. Chromosome 2 (mouse)[2] Band 2|2 C1.1 Start 60,082,337 bp [2] End 60,114,832 bp [2]
Gene ontology Molecular function Cellular component Biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 2: 159.77 – 159.8 Mb Chr 2: 60.08 – 60.11 Mb PubMed search[3] [4] Wikidata
The CD302 antigen also known as C-type lectin domain family 13 member A is a protein that in humans is encoded by the CD302 gene .[5] [6]
Function [ ]
CD302 is a C-type lectin receptor involved in cell adhesion and migration , as well as endocytosis and phagocytosis .[7]
References [ ]
^ a b c GRCh38: Ensembl release 89: ENSG00000241399 - Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000060703 - Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S (1994). "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1" . DNA Res . 1 (1): 27–35. doi :10.1093/dnares/1.1.27 . PMID 7584026 .
^ Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S (1994). "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement)" . DNA Res . 1 (1): 47–56. doi :10.1093/dnares/1.1.47 . PMID 7584028 .
^ Kato M, Khan S, d'Aniello E, McDonald KJ, Hart DN (November 2007). "The novel endocytic and phagocytic C-Type lectin receptor DCL-1/CD302 on macrophages is colocalized with F-actin, suggesting a role in cell adhesion and migration" . J. Immunol . 179 (9): 6052–63. doi :10.4049/jimmunol.179.9.6052 . PMID 17947679 .
External links [ ]
Human CD302 genome location and CD302 gene details page in the UCSC Genome Browser .
Further reading [ ]
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4" . Nature . 434 (7034): 724–31. doi :10.1038/nature03466 . PMID 15815621 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 . PMID 15489334 .
Yang S, Noble CG, Yang D (2009). "Characterization of DLC1-SAM equilibrium unfolding at the amino acid residue level". Biochemistry . 48 (19): 4040–9. doi :10.1021/bi9000936 . PMID 19317456 .
Kato M, Khan S, Gonzalez N, et al. (2003). "Hodgkin's lymphoma cell lines express a fusion protein encoded by intergenically spliced mRNA for the multilectin receptor DEC-205 (CD205) and a novel C-type lectin receptor DCL-1" . J. Biol. Chem . 278 (36): 34035–41. doi :10.1074/jbc.M303112200 . PMID 12824192 .
Bonaldo MF, Lennon G, Soares MB (1996). "Normalization and subtraction: two approaches to facilitate gene discovery" . Genome Res . 6 (9): 791–806. doi :10.1101/gr.6.9.791 . PMID 8889548 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
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Protein : lectins
Animal
Plant
Categories :
Genes on human chromosome 2 Human chromosome 2 gene stubs