2-Methyl-MDA
From Wikipedia, the free encyclopedia
Clinical data | |
---|---|
Routes of administration | Oral |
ATC code |
|
Legal status | |
Legal status |
|
Identifiers | |
CAS Number |
|
PubChem CID | |
ChemSpider |
|
ChEMBL | |
CompTox Dashboard (EPA) | |
Chemical and physical data | |
Formula | C11H15NO2 |
Molar mass | 193.246 g·mol−1 |
3D model (JSmol) | |
show
InChI
| |
NY (what is this?) |
2-Methyl-3,4-methylenedioxyamphetamine (2-methyl-MDA) is an entactogen[citation needed] and psychedelic[citation needed] drug of the amphetamine class. It acts as a selective serotonin releasing agent (SSRA), with IC50 values of 93nM, 12,000nM, and 1,937nM for serotonin, dopamine, and norepinephrine efflux.[1] 2-Methyl-MDA is more potent than MDA and 5-methyl-MDA.[1] However, it is slightly more selective for serotonin over dopamine and norepinephrine release in comparison to 5-methyl-MDA.[1]
References[]
- ^ Jump up to: a b c Parker MA, Marona-Lewicka D, Kurrasch D, Shulgin AT, Nichols DE (March 1998). "Synthesis and pharmacological evaluation of ring-methylated derivatives of 3,4-(methylenedioxy)amphetamine (MDA)". Journal of Medicinal Chemistry. 41 (6): 1001–5. CiteSeerX 10.1.1.688.9559. doi:10.1021/jm9705925. PMID 9526575.
show
Empathogens/entactogens | |
---|---|
Phenylalkyl- amines (other than cathinones) |
|
Cyclized phenyl- alkylamines | |
Cathinones |
|
Tryptamines |
|
Chemical classes |
|
show
| |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DRAs |
| ||||||||||||||
NRAs |
| ||||||||||||||
SRAs |
| ||||||||||||||
Others |
| ||||||||||||||
See also: Receptor/signaling modulators • Monoamine reuptake inhibitors • Adrenergics • Dopaminergics • Serotonergics • Monoamine metabolism modulators • Monoamine neurotoxins |
show
Phenethylamines | |
---|---|
Phenethylamines |
|
Amphetamines |
|
Phentermines |
|
Cathinones |
|
Phenylisobutylamines | |
Phenylalkylpyrrolidines | |
Catecholamines (and close relatives) |
|
Miscellaneous |
|
Retrieved from ""
Categories:
- Drugs not assigned an ATC code
- Substituted amphetamines
- Benzodioxoles
- Entactogens and empathogens
- Serotonin releasing agents
Hidden categories:
- Drugs with non-standard legal status
- Articles with changed CASNo identifier
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Articles without UNII source
- Drugboxes which contain changes to verified fields
- All articles with unsourced statements
- Articles with unsourced statements from July 2012