Dynorphin A
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Dynorphin 1-13
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Chemical formula
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C75H126N24O15 |
| Molar mass | 1603.95474 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 (what is   ?)
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Dynorphin A is a dynorphin, an endogenous opioid peptide with the amino acid sequence: Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys.
Dynorphin A1–8 is a truncated form of dynorphin A with the amino acid sequence: Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile.[2][3] Dynorphin A1–8 is an agonist at the mu-, kappa-, and delta-opioid receptors;[3] it has the highest binding affinity for the kappa-opioid receptor.[3]
References[]
- ^ Dynorphin 1-13 - Compound Summary, PubChem.
- ^ "Dynorphin A 1-8". HMDB Version 4.0. Human Metabolome Database. 27 September 2017. Retrieved 20 October 2017.
- ^ a b c "Dynorphin A-(1-8): Biological activity". IUPHAR/BPS Guide to PHARMACOLOGY. International Union of Basic and Clinical Pharmacology. Retrieved 20 October 2017.
Principal endogenous agonists at κ receptor
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Categories:
- Neuropeptides
- Kappa-opioid receptor agonists
- Opioid peptides
- Organic compound stubs