Methorphan

Racemethorphan
Clinical data
ATC code	None;
Legal status
Legal status	AU: S9 (Prohibited substance) ; CA: Schedule I ; DE: Anlage I (Authorized scientific use only) ; UK: Class A ; US: Schedule II ; UN: Psychotropic Schedule I ;
Identifiers
	IUPAC name 3-Methoxy-17-methylmorphinan;
CAS Number	510-53-2 ;
PubChem CID	3008;
ChemSpider	2901 ;
UNII	8YB8F78WM1;
ChEBI	CHEBI:146177;
ChEMBL	ChEMBL22207 ;
Chemical and physical data
Formula	C18H25NO
Molar mass	271.404 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN1CCC23CCCCC2C1CC4=C3C=C(C=C4)OC;
	InChI InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3 ; Key:MKXZASYAUGDDCJ-UHFFFAOYSA-N ;
	(what is this?)

Methorphan comes in two isomeric forms, each with differing pharmacology and effects:

Dextromethorphan - An over-the-counter cough suppressant, as well as dissociative hallucinogen.
Levomethorphan - A potent opioid analgesic that was never clinically developed; a prodrug of the powerful opioid agonist analgesic levorphanol (Levo-Dromoran).

Racemethorphan refers to the racemic mixture of both of these stereoisomers. It is listed under the Single Convention on Narcotic Drugs 1961 and is therefore listed in the United States as a Controlled Substance, specifically as a Narcotic in Schedule II with an ACSCN of 9732 and an annual aggregate manufacturing quota of 3 grams in 2014.^[1] The salts in use are the hydrobromide (free base conversion ratio 0.770) and the tartrate (0.644)

References[]

^ "Conversion Factors for Controlled Substances". www.deadiversion.usdoj.gov.

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[1] "Conversion Factors for Controlled Substances". www.deadiversion.usdoj.gov.

[1]

Methorphan

See also[]

References[]