Oxymorphone-3-methoxynaltrexonazine

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Oxymorphone-3-methoxynaltrexonazine
Oxymorphone-3-methoxynaltrexonazine.svg
Identifiers
  • (7Z)-7-[(Z)-[3-(cyclopropylmethyl)-4a-hydroxy-9-methoxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ylidene]hydrazinylidene]-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC38H44N4O6
Molar mass652.792 g·mol−1
3D model (JSmol)
  • CN1CCC23C4C(=NN=C5CCC6(C7CC8=C9C6(C5OC9=C(C=C8)OC)CCN7CC5CC5)O)CCC2(C1CC1=C3C(=C(C=C1)O)O4)O
InChI
  • InChI=1S/C38H44N4O6/c1-41-15-13-35-29-21-5-7-25(43)31(29)47-33(35)23(9-11-37(35,44)27(41)17-21)39-40-24-10-12-38(45)28-18-22-6-8-26(46-2)32-30(22)36(38,34(24)48-32)14-16-42(28)19-20-3-4-20/h5-8,20,27-28,33-34,43-45H,3-4,9-19H2,1-2H3/b39-23-,40-24-
  • Key:ORPKJVOXWSMNDJ-XCKRHRGHSA-N

Oxymorphone-3-methoxynaltrexonazine (OM-3-MNZ) is a morphinan-based opioid that acts as a selective μ-opioid receptor agonist, unlike the closely related mixed agonist-antagonist Oxymorphonenaltrexonazine.[1]

See also[]

References[]

  1. ^ Galetta S, Hahn EF, Nishimura S, Pasternak GW (August 1987). "Oxymorphone-naltrexonazine, a mixed opiate agonist-antagonist". Life Sciences. 41 (6): 783–7. doi:10.1016/0024-3205(87)90459-0. PMID 2441221.
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