Clocinnamox
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Preferred IUPAC name
(2E)-3-(4-Chlorophenyl)-N-[(4R,4aS,7aR,12bR)-3-(cyclopropylmethyl)-9-hydroxy-7-oxo-1,2,3,4,5,6,7,7a-octahydro-4aH-4,12-methano[1]benzofuro[3,2-e]isoquinolin-4a-yl]prop-2-enamide | |
Other names
Chlorocinnamoylaminodihydronormorphinone
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CAS Number
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3D model (JSmol)
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ChEMBL | |
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PubChem CID
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InChI
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Properties | |
Chemical formula
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C29H29ClN2O4 |
Molar mass | 505.01 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
Clocinnamox is a selective, irreversible μ-opioid receptor antagonist.[2]
References[]
- ^ Chambers, Michael. "ChemIDplus - 122566-12-5 - RAURUSFBVQLAPW-VHDUHSAMSA-N - RX 809055AX - Similar structures search, synonyms, formulas, resource links, and other chemical information". chem.nlm.nih.gov.
- ^ Filho, CB; Del Fabbro, L; De Gomes, MG; Goes, AT; Souza, LC; Boeira, SP; Jesse, CR (2013). "Kappa-opioid receptors mediate the antidepressant-like activity of hesperidin in the mouse forced swimming test". European Journal of Pharmacology. 698 (1–3): 286–91. doi:10.1016/j.ejphar.2012.11.003. PMID 23178563.
Categories:
- Acrylamides
- Heterocyclic compounds with 5 rings
- Chloroarenes
- Oxygen heterocycles
- Mu-opioid receptor antagonists
- Nitrogen heterocycles
- Amides
- Cyclopropyl compounds
- Analgesic stubs