3-Methyl-PCP

3'-Me-PCP
Legal status
Legal status	CA: Schedule I ; DE: NpSG (Industrial and scientific use only) ; UK: Class B ;
Identifiers
	IUPAC name 1-[1-(3-methylphenyl)cyclohexyl]piperidine;
CAS Number	2201-30-1 ;
PubChem CID	611899;
ChemSpider	531905;
UNII	Y9XHS38QLZ;
Chemical and physical data
Formula	C18H27N
Molar mass	257.421 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1=CC(=CC=C1)C2(CCCCC2)N3CCCCC3;
	InChI InChI=1S/C18H27N/c1-16-9-8-10-17(15-16)18(11-4-2-5-12-18)19-13-6-3-7-14-19/h8-10,15H,2-7,11-14H2,1H3; Key:BMFKUCGCXMDGBK-UHFFFAOYSA-N;

3-Methyl-PCP (3'-Methyl-PCP, meta-Methyl-PCP) is a recreational designer drug with dissociative effects. It is an arylcyclohexylamine derivative, related to drugs such as 3'-MeO-PCP and 3'-Me-PCPy.^[1]^[2] It was first synthesised in the 1960s,^[3] but was only identified on the illicit market in Hungary in September 2020,^[4] and was made illegal in Hungary in April 2021.^[5]

References[]

^ Linders J, Furlano DC, Mattson MV, Jacobson AE, Rice KC (February 2010). "Synthesis and preliminary biochemical evaluation of novel derivatives of PCP". Letters in Drug Design & Discovery. 7 (2): 79–87. doi:10.2174/157018010790225813.
^ Wallach J, De Paoli G, Adejare A, Brandt SD. Preparation and analytical characterization of 1-(1-phenylcyclohexyl)piperidine (PCP) and 1-(1-phenylcyclohexyl)pyrrolidine (PCPy) analogues. Drug Test. Anal., 1 Jul 2014, 6(7-8): 633-650. doi:10.1002/dta.1468
^ Maddox VH, Godefroi EF, Parcell RF (March 1965). "The synthesis of phencyclidine and other 1-arylcyclohexylamines". Journal of Medicinal Chemistry. 8: 230–5. doi:10.1021/jm00326a019. PMID 14332667.
^ Jankovic M (28 January 2021). "EU Early Warning System" (PDF). Der Koordinator für Psychiatrie, Sucht- und Drogenfragen und der Beauftragte für Sucht- und Drogenfragen der Stadt Wien.
^ "Amendment of Minister for Human Capacities Decree No 55/2014 of 30 December 2014 on substances or groups of compounds classified as new psychoactive substances, 2021/225/HU".

This hallucinogen-related article is a stub. You can help Wikipedia by .

[1] Linders J, Furlano DC, Mattson MV, Jacobson AE, Rice KC (February 2010). "Synthesis and preliminary biochemical evaluation of novel derivatives of PCP". Letters in Drug Design & Discovery. 7 (2): 79–87. doi:10.2174/157018010790225813.

[2] Wallach J, De Paoli G, Adejare A, Brandt SD. Preparation and analytical characterization of 1-(1-phenylcyclohexyl)piperidine (PCP) and 1-(1-phenylcyclohexyl)pyrrolidine (PCPy) analogues. Drug Test. Anal., 1 Jul 2014, 6(7-8): 633-650. doi:10.1002/dta.1468

[pmid14332667-3] Maddox VH, Godefroi EF, Parcell RF (March 1965). "The synthesis of phencyclidine and other 1-arylcyclohexylamines". Journal of Medicinal Chemistry. 8: 230–5. doi:10.1021/jm00326a019. PMID 14332667.

[4] Jankovic M (28 January 2021). "EU Early Warning System" (PDF). Der Koordinator für Psychiatrie, Sucht- und Drogenfragen und der Beauftragte für Sucht- und Drogenfragen der Stadt Wien.

[5] "Amendment of Minister for Human Capacities Decree No 55/2014 of 30 December 2014 on substances or groups of compounds classified as new psychoactive substances, 2021/225/HU".

[1]

[2]

[3]

[4]

[5]

v t Sigma receptor modulators
σ₁	Agonists: 3-PPP 4-PPBP 5-MeO-DMT Alazocine (SKF-10047) Amantadine Arketamine BD-1052 Blarcamesine Captodiame Citalopram CGRP Cloperastine Cocaine Cutamesine (SA-4503) Cyclazocine Dehydroepiandrosterone (DHEA) (prasterone) Dehydroepiandrosterone sulfate (DHEA-S) (prasterone sulfate) Dextrallorphan Dextromethorphan (DXM) Dextrorphan (DXO) Dimemorfan Dimethyltryptamine (DMT) Ditolylguanidine (DTG) Donepezil Eliprodil Escitalopram Fabomotizole (afobazole) Fluoxetine Fluvoxamine Ifenprodil Igmesine (JO-1784) Ketamine L-687384 MDMA (midomafetamine) Memantine Methamphetamine Methoxetamine Methylphenidate Nepinalone Neuropeptide Y Noscapine Opipramol Pentazocine Pentoxyverine (carbetapentane) PRE-084 Pregnenolone Pregnenolone sulfate Pridopidine Racemethorphan (methorphan) Racemorphan (morphanol) Antagonists: 3-PPP AC-927 BD-1008 BD-1031 BD-1047 BD-1060 BD-1063 BD-1067 BMY-14802 (BMS-181100) CM-156 E-52862 (S1RA) Haloperidol NE-100 Panamesine (EMD-57455) Pentazocine Progesterone Rimcazole (BW-234U) Sertraline Allosteric modulators: Phenytoin; Positive: Methylphenylpiracetam Unknown/unsorted: 3-MeO-PCP 4C-T-2 4-MeO-PCP 5-MeO-DALT 5-MeO-DiPT Amitriptyline Chlorpromazine Clemastine Clomipramine Clorgiline D-Deprenyl DiPT DPT Ibogaine Imipramine Nemonapride Noribogaine RS-67,333 RTI-55 Saffron Safinamide Selegiline Trifluoperazine W-18 YKP10A
σ₂	Agonists: 3-PPP Arketamine BD-1047 BD1063 Ditolylguanidine (DTG) Haloperidol Ifenprodil Ketamine MDMA (midomafetamine) Methamphetamine Opipramol PB-28 Phencyclidine Siramesine (Lu 28-179) Antagonists: AC-927 BD-1008 BD-1067 CM-156 MIN-101 Panamesine (EMD-57455) Unknown/unsorted: 3-MeO-PCE 4-MeO-PCP 5-MeO-DALT 5-MeO-DiPT Clemastine DiPT DPT Ibogaine Nemonapride Nepinalone Noribogaine Pentazocine RS-67,333 Safinamide TMA W-18
Unsorted	Agonists: Berberine Ethylketazocine Fourphit Metaphit Naluzotan Tapentadol Tenocyclidine Antagonists: Lamotrigine Naloxone Allosteric modulators: SKF-83959 Unknown/unsorted: 18-Methoxycoronaridine Butaclamol Caramiphen Chlorphenamine (chlorpheniramine) Chlorpromazine Cinnarizine Clocapramine Dezocine Hypericin (St. John's wort) Fluphenazine Gevotroline (WY-47384) Mepyramine (pyrilamine) Molindone Perphenazine Pimozide Proadifen Promethazine Propranolol Quinidine Remoxipride Tiospirone (BMY-13859) Venlafaxine
See also: Receptor/signaling modulators

Legal status

Legal status	CA: Schedule I DE: NpSG (Industrial and scientific use only) UK: Class B
Identifiers
IUPAC name 1-[1-(3-methylphenyl)cyclohexyl]piperidine
CAS Number	2201-30-1^Y
PubChem CID	611899
ChemSpider	531905
UNII	Y9XHS38QLZ
Chemical and physical data
Formula	C₁₈H₂₇N
Molar mass	257.421 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC1=CC(=CC=C1)C2(CCCCC2)N3CCCCC3
InChI InChI=1S/C18H27N/c1-16-9-8-10-17(15-16)18(11-4-2-5-12-18)19-13-6-3-7-14-19/h8-10,15H,2-7,11-14H2,1H3 Key:BMFKUCGCXMDGBK-UHFFFAOYSA-N

3-Methyl-PCP

See also[]

References[]