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Befuraline ATC code show
1-benzofuran-2-yl(4-benzylpiperazin-1-yl)methanone
CAS Number PubChem CID ChemSpider UNII ChEMBL CompTox Dashboard (EPA ) Formula C 20 H 20 N 2 O 2 Molar mass 320.392 g·mol−1 3D model (JSmol ) show
O=C(N1CCN(CC1)CC2=CC=CC=C2)C3=CC4=C(C=CC=C4)O3
show
InChI=1S/C20H20N2O2/c23-20(19-14-17-8-4-5-9-18(17)24-19)22-12-10-21(11-13-22)15-16-6-2-1-3-7-16/h1-9,14H,10-13,15H2
Y Key:SRIJFPBZWUFLFD-UHFFFAOYSA-N
Y
Befuraline (DIV-154 ) is a psychoactive drug and member of the piperazine chemical class which was developed in Germany in the 1970s.[1] Befuraline has stimulant and antidepressant effects and has seen some use in Germany and France , although it has never become widely used.[2] Befuraline's active metabolite benzylpiperazine is responsible for its effects.[citation needed ]
See also [ ]
References [ ]
^ Boksay IJ, Popendiker K, Weber RO, Söder A (1979). "Synthesis and pharmacological activity of befuraline (N-benzo[b]furan-2-ylcarbonyl-N'-benzylpiperazine), a new antidepressant compound". Arzneimittel-Forschung . 29 (2): 193–204. PMID 582130 .
^ Gastpar M, Gastpar G, Gilsdorf U (November 1985). "Befuraline, its safety and efficacy in depressed inpatients". Pharmacopsychiatry . 18 (6): 351–5. doi :10.1055/s-2007-1017396 . PMID 4089015 .
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