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Isopropamide MedlinePlus a694006 Routes of administration Oral ATC code Legal status
US : ℞-only and Unscheduled
In general: unscheduled
4-amino-N,N -diisopropyl-N -methyl-4-oxo-3,3-diphenylbutan-1-aminium
CAS Number PubChem CID DrugBank ChemSpider UNII ChEMBL CompTox Dashboard (EPA ) ECHA InfoCard 100.028.470 Formula C 23 H 33 N 2 O + Molar mass 353.530 g·mol−1 3D model (JSmol )
O=C(N)C(c1ccccc1)(c2ccccc2)CC[N+](C(C)C)(C(C)C)C
InChI=1S/C23H32N2O/c1-18(2)25(5,19(3)4)17-16-23(22(24)26,20-12-8-6-9-13-20)21-14-10-7-11-15-21/h6-15,18-19H,16-17H2,1-5H3,(H-,24,26)/p+1
Y Key:JTPUMZTWMWIVPA-UHFFFAOYSA-O
Y
N Y (what is this?)
Isopropamide (R79 ) is a long-acting anticholinergic drug . It is used in the treatment of peptic ulcers and other gastrointestinal disorders involving hyperacidity (gastrointestinal acidosis ) and hypermotility. Chemically, it contains a quaternary ammonium group. It is most often provided as an iodide salt, but is also available as a bromide or chloride salt. It was discovered at Janssen Pharmaceutica in 1954.
References [ ]
Further reading [ ]
Seeherman R (October 1957). "Isopropamide iodide: a long-acting anticholinergic". Delaware Medical Journal . 29 (10): 265–9. PMID 13473394 .
Boss Jr EG, Buchanan GC (November 1957). "Effect of isopropamide iodide on basal gastric secretion in the human". Gastroenterology . 33 (5): 730–6. PMID 13480414 .
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