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Timepidium bromide AHFS /Drugs.com International Drug Names Routes of administration SC, IM, IV ATC code Legal status
In general: ℞ (Prescription only)
3-(di-2-thienylmethylene)-5-methoxy-1,1-dimethylpiperidinium bromide
CAS Number PubChem CID ChemSpider UNII CompTox Dashboard (EPA ) Formula C 17 H 22 Br N O S 2 Molar mass 400.39 g·mol−1 3D model (JSmol )
C[N+]1(CC(CC(=C(C2=CC=CS2)C3=CC=CS3)C1)OC)C.[Br-]
InChI=1S/C17H22NOS2.BrH/c1-18(2)11-13(10-14(12-18)19-3)17(15-6-4-8-20-15)16-7-5-9-21-16;/h4-9,14H,10-12H2,1-3H3;1H/q+1;/p-1
N Key:QTSXMEPZSHLZFF-UHFFFAOYSA-M
N
N Y (what is this?)
Timepidium bromide (INN ) is an anticholinergic . It is used in the symptomatic treatment of visceral spasms.[1] It is also used to relieve pain associated with various gastrointestinal disorders.[2] The quaternary nitrogen prevents it from crossing the blood brain barrier , so it is peripherally acting with no central side effects.
The same compound sans the quaternary methyl group and the methoxy ether is called tipepidine .[3]
References [ ]
Drugs for functional bowel disorders
Antimuscarinics
Tertiary amino group Quaternary ammonium compounds
Phosphodiesterase inhibitors Acting on serotonin receptors Other
Belladonna and derivatives (antimuscarinics )Propulsives
mAChRs
Agonists Antagonists
3-Quinuclidinyl benzilate
4-DAMP
Aclidinium bromide (+formoterol )
Abediterol
AF-DX 384
Ambutonium bromide
Anisodamine
Anisodine
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Benactyzine
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Benzilylcholine mustard
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Biperiden
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CAR-226,086
CAR-301,060
CAR-302,196
CAR-302,282
CAR-302,668
Caramiphen
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CS-27349
Cyclobenzaprine
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EA-3167
EA-3443
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Fenpiverinium
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PD-102,807
PD-0298029
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Tiemonium iodide
Timepidium bromide
Tiotropium bromide
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Tricyclic antidepressants (e.g., amitriptyline (+perphenazine ), amitriptylinoxide , butriptyline , cidoxepin , clomipramine , desipramine , , dibenzepin , dosulepin (dothiepin) , doxepin , imipramine , lofepramine , nitroxazepine , northiaden (desmethyldosulepin) , nortriptyline , protriptyline , quinupramine , trimipramine )
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Typical antipsychotics (e.g., chlorpromazine , chlorprothixene , cyamemazine (cyamepromazine) , loxapine , mesoridazine , thioridazine )
Umeclidinium bromide (+vilanterol )
WIN-2299
Xanomeline
Precursors (and prodrugs ) See also: Receptor/signaling modulators • Nicotinic acetylcholine receptor modulators • Acetylcholine metabolism/transport modulators
Categories :
Muscarinic antagonists Thiophenes Quaternary ammonium compounds Piperidines Ethers Alkene derivatives Bromides Peripherally selective drugs Gastrointestinal system drug stubs Hidden categories:
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