From Wikipedia, the free encyclopedia
Piroheptine |
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AHFS/Drugs.com | International Drug Names |
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Routes of administration | Oral |
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ATC code | |
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Legal status |
- In general: ℞ (Prescription only)
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3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-1-ethyl-2-methylpyrrolidine
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CAS Number | |
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PubChem CID | |
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ChemSpider | |
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UNII | |
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KEGG | |
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ChEBI | |
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Formula | C22H25N |
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Molar mass | 303.449 g·mol−1 |
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3D model (JSmol) | |
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CCN1CCC(=C2C3=CC=CC=C3CCC4=CC=CC=C42)C1C
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InChI=1S/C22H25N/c1-3-23-15-14-19(16(23)2)22-20-10-6-4-8-17(20)12-13-18-9-5-7-11-21(18)22/h4-11,16H,3,12-15H2,1-2H3 Key:NKJQZSDCCLDOQH-UHFFFAOYSA-N
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Piroheptine (brand name Trimol) is an anticholinergic and antihistamine used as an antiparkinsonian agent.
References[]
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Dopaminergics | DA precursors | |
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DA receptor agonists |
- Ergoline: Bromocriptine
- Cabergoline
- Dihydroergocryptine
- Lisuride
- Pergolide
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MAO-B inhibitors | |
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COMT inhibitors |
- Entacapone
- Opicapone
- Tolcapone
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AAAD inhibitors | |
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Anticholinergics | |
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Others |
- Amantadine
- Budipine
- Istradefylline
- Methylxanthines (e.g., caffeine)
- Rimantadine
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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H1 | Agonists |
- 2-Pyridylethylamine
- Betahistine
- Histamine
- HTMT
- L-Histidine
- UR-AK49
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Antagonists |
- Others: Atypical antipsychotics (e.g., aripiprazole, asenapine, brexpiprazole, brilaroxazine, clozapine, iloperidone, olanzapine, paliperidone, quetiapine, risperidone, ziprasidone, zotepine)
- Phenylpiperazine antidepressants (e.g., hydroxynefazodone, nefazodone, trazodone, triazoledione)
- Tetracyclic antidepressants (e.g., amoxapine, loxapine, maprotiline, mianserin, mirtazapine, oxaprotiline)
- Tricyclic antidepressants (e.g., amitriptyline, butriptyline, clomipramine, desipramine, dosulepin (dothiepin), doxepin, imipramine, iprindole, lofepramine, nortriptyline, protriptyline, trimipramine)
- Typical antipsychotics (e.g., chlorpromazine, flupenthixol, fluphenazine, loxapine, perphenazine, prochlorperazine, thioridazine, thiothixene)
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H2 | |
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H3 | Agonists |
- α-Methylhistamine
- Cipralisant
- Histamine
- Imetit
- Immepip
- Immethridine
- L-Histidine
- Methimepip
- Proxyfan
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Antagonists | |
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H4 | Agonists |
- 4-Methylhistamine
- α-Methylhistamine
- Histamine
- L-Histidine
- OUP-16
- VUF-8430
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Antagonists | |
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See also: Receptor/signaling modulators • Monoamine metabolism modulators • Monoamine reuptake inhibitors |
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mAChRs | Agonists | |
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Antagonists |
- 3-Quinuclidinyl benzilate
- 4-DAMP
- Aclidinium bromide (+formoterol)
- Abediterol
- AF-DX 384
- Ambutonium bromide
- Anisodamine
- Anisodine
- Antihistamines (first-generation) (e.g., brompheniramine, buclizine, captodiame, chlorphenamine (chlorpheniramine), cinnarizine, clemastine, cyproheptadine, dimenhydrinate, dimetindene, diphenhydramine, doxylamine, meclizine, mequitazine, perlapine, phenindamine, pheniramine, phenyltoloxamine, promethazine, propiomazine, triprolidine)
- Atropine
- Atropine methonitrate
- Atypical antipsychotics (e.g., clozapine, fluperlapine, olanzapine (+fluoxetine), , quetiapine, tenilapine, zotepine)
- Benactyzine
- Benzatropine (benztropine)
- Benzilone
- Benzilylcholine mustard
- Benzydamine
- Biperiden
- Bornaprine
- Camylofin
- CAR-226,086
- CAR-301,060
- CAR-302,196
- CAR-302,282
- CAR-302,668
- Caramiphen
- Cimetropium bromide
- Clidinium bromide
- Cloperastine
- CS-27349
- Cyclobenzaprine
- Cyclopentolate
- Darifenacin
- Desfesoterodine
- Dexetimide
- Dicycloverine (dicyclomine)
- Dihexyverine
- Difemerine
- Diphemanil metilsulfate
- Ditran
- Drofenine
- EA-3167
- EA-3443
- EA-3580
- EA-3834
- Emepronium bromide
- Etanautine
- Etybenzatropine (ethybenztropine)
- Fenpiverinium
- Fentonium bromide
- Fesoterodine
- Flavoxate
- Glycopyrronium bromide (+beclometasone/formoterol, +indacaterol)
- Hexocyclium
- Himbacine
- Homatropine
- Imidafenacin
- Ipratropium bromide (+salbutamol)
- Isopropamide
- Hyoscyamine
- Mamba toxin 3
- Mamba toxin 7
- Mazaticol
- Mebeverine
- Meladrazine
- Mepenzolate
- Methantheline
- Methoctramine
- Methylatropine
- Methylhomatropine
- Methylscopolamine
- Metixene
- Muscarinic toxin 7
- N-Ethyl-3-piperidyl benzilate
- N-Methyl-3-piperidyl benzilate
- Nefopam
- Octatropine methylbromide (anisotropine methylbromide)
- Orphenadrine
- Otenzepad (AF-DX 116)
- Otilonium bromide
- Oxapium iodide
- Oxitropium bromide
- Oxybutynin
- Oxyphencyclimine
- Oxyphenonium bromide
- PD-102,807
- PD-0298029
- Penthienate
- Pethidine
- Phenglutarimide
- Phenyltoloxamine
- Pipenzolate bromide
- Piperidolate
- Pirenzepine
- Piroheptine
- Pizotifen
- Poldine
- Pridinol
- Prifinium bromide
- Procyclidine
- Profenamine (ethopropazine)
- Propantheline bromide
- Propiverine
- Quinidine
- 3-Quinuclidinyl thiochromane-4-carboxylate
- Revefenacin
- Rociverine
- Scopolamine (hyoscine)
- Scopolamine butylbromide (hyoscine butylbromide)
- Sofpironium bromide
- Solifenacin
- SSRIs (e.g., femoxetine, paroxetine)
- Telenzepine
- Terodiline
- Tetracyclic antidepressants (e.g., amoxapine, maprotiline, mianserin, mirtazapine)
- Tiemonium iodide
- Timepidium bromide
- Tiotropium bromide
- Tofenacin
- Tolterodine
- Tricyclic antidepressants (e.g., amitriptyline (+perphenazine), amitriptylinoxide, butriptyline, cidoxepin, clomipramine, desipramine, , dibenzepin, dosulepin (dothiepin), doxepin, imipramine, lofepramine, nitroxazepine, northiaden (desmethyldosulepin), nortriptyline, protriptyline, quinupramine, trimipramine)
- Tridihexethyl
- Trihexyphenidyl
- Trimebutine
- Tropatepine
- Tropicamide
- Trospium chloride
- Typical antipsychotics (e.g., chlorpromazine, chlorprothixene, cyamemazine (cyamepromazine), loxapine, mesoridazine, thioridazine)
- Umeclidinium bromide (+vilanterol)
- WIN-2299
- Xanomeline
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Precursors (and prodrugs) |
- Acetyl-coA
- Adafenoxate
- Choline (lecithin)
- Citicoline
- Cyprodenate
- Dimethylethanolamine
- Glycerophosphocholine
- Meclofenoxate (centrophenoxine)
- Phosphatidylcholine
- Phosphatidylethanolamine
- Phosphorylcholine
- Pirisudanol
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See also: Receptor/signaling modulators • Nicotinic acetylcholine receptor modulators • Acetylcholine metabolism/transport modulators |
Categories:
- Drugs not assigned an ATC code
- Antihistamines
- Antiparkinsonian agents
- Dibenzocycloheptenes
- H1 receptor antagonists
- Muscarinic antagonists
- Pyrrolidines
- Nervous system drug stubs
Hidden categories:
- Drugs with non-standard legal status
- Chemical pages without DrugBank identifier
- Multiple chemicals in Infobox drug
- Chemicals using indexlabels
- Chemical articles with multiple CAS registry numbers
- All stub articles