Not to be confused with Methoxetamine .
Methoxyketamine
Names
IUPAC name
2-(2-Methoxyphenyl)-2-(methylamino)cyclohexanone
Identifiers
CAS Number
3D model (JSmol )
ChemSpider
UNII
InChI=1S/C14H19NO2/c1-15-14(10-6-5-9-13(14)16)11-7-3-4-8-12(11)17-2/h3-4,7-8,15H,5-6,9-10H2,1-2H3
Key: OYAUVHORXFUVAJ-UHFFFAOYSA-N
InChI=1/C14H19NO2/c1-15-14(10-6-5-9-13(14)16)11-7-3-4-8-12(11)17-2/h3-4,7-8,15H,5-6,9-10H2,1-2H3
Key: OYAUVHORXFUVAJ-UHFFFAOYAM
Properties
Chemical formula
C 14 H 19 N O 2
Molar mass
233.311 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Chemical compound
Methoxyketamine or 2-MeO-2-deschloroketamine is a designer drug of the arylcyclohexylamine class first reported in 1963.[1] It is an analog of ketamine in which the chlorine atom has been replaced with a methoxy group . Its synthesis by rearrangement of an amino ketone has been reported.[2] As an arylcyclohexylamine, methoxyketamine most likely functions as an NMDA receptor antagonist . It produces sedative, hallucinogenic, and (at high doses) anesthetic effects, but with a lower potency than ketamine itself.
See also [ ]
References [ ]
^ BE 634208 , Stevens, Calvin L., "Amino ketones", published 1963
^ Stevens, Calvin L.; Thuillier, Andre; Taylor, K. Grant; Daniher, Francis A.; Dickerson, James P.; Hanson, Harry T.; Nielsen, Norman A.; Tikotkar, N. A.; Weier, Richard M. (1966). "Amino Ketone Rearrangements. VII.1 Synthesis of 2-Methylamino-2-Substituted Phenylcyclohexanones". The Journal of Organic Chemistry . 31 (8): 2601. doi :10.1021/jo01346a034 .
Hallucinogens
Psychedelics (5-HT2A agonists)
Benzofurans
2C-B-FLY
2CBFly-NBOMe
5-MeO-BFE
5-MeO-DiBF
Bromo-DragonFLY
F-2
F-22
TFMFly
Lyserg‐ amides
1B-LSD
1cP-LSD
1P-ETH-LAD
1P-LSD
1V-LSD
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Phenethyl‐ amines
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α-MT
x -DALT
(Daltacetin) 4-AcO-DALT
5-MeO-DALT
DALT
x -DET
(Ethacetin) 4-AcO-DET
(Ethocin) 4-HO-DET
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(T-9) DET
(Ethocybin) 4-PO-DET
x -DiPT
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7,N,N-TMT
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DMT
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; Positive allosteric modulators: Cyclothiazide
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Antagonists:
CNQX
Dasolampanel
DNQX
Kaitocephalin
Kynurenic acid
Licostinel (ACEA-1021)
NBQX
NS102
Selurampanel
Tezampanel
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Enflurane
Ethanol (alcohol)
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See also: Receptor/signaling modulators
Metabotropic glutamate receptor modulators
Glutamate metabolism/transport modulators
Group I
mGluR1
Agonists: ACPD
DHPG
Glutamate
Ibotenic acid
Quisqualic acid
Ro01-6128
Ro67-4853
Theanine
mGluR5
Agonists: ACPD
ADX-47273
CDPPB
CHPG
DHPG
Glutamate
Ibotenic acid
Quisqualic acid
Group II
Group III
mGluR4 mGluR6
Agonists: Glutamate
L -AP4
mGluR7
Agonists: AMN082
Glutamate
L -AP4
mGluR8
See also: Receptor/signaling modulators • Ionotropic glutamate receptor modulators • Glutamate metabolism/transport modulators