N-Phenethylnordesomorphine
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Formula | C24H27NO2 |
Molar mass | 361.485 g·mol−1 |
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N-Phenethylnordesomorphine is an opiate analgesic drug derived from desomorphine by replacing the N-methyl group with β-phenethyl. Since desomorphine is already around eight times more potent than morphine, the additional boost in binding affinity produced by using the larger phenethyl group makes N-phenethylnordesomorphine a highly potent analgesic drug, some 85x more potent than morphine,[1] and a similar strength to the closely related morphinan derivative phenomorphan.
See also[]
- 14-Cinnamoyloxycodeinone
- 14-Phenylpropoxymetopon
- 7-PET
- N-Phenethyl-14-ethoxymetopon
- N-Phenethylnormorphine
- RAM-378
- Ro4-1539
References[]
- ^ Casy AF, Parfitt RY (1986). Opioid analgesics, chemistry and receptors. New York: Plenum Press. pp. 37–38. ISBN 978-0-306-42130-3.
Categories:
- Morphinans
- Semisynthetic opioids
- Mu-opioid receptor agonists
- Analgesic stubs