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Pipecuronium bromide AHFS /Drugs.com International Drug Names ATC code show
(2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)-2,16-bis(4,4-dimethylpiperazin-4-ium-1-yl)androstane dibromide
CAS Number PubChem CID ChemSpider UNII KEGG ChEMBL CompTox Dashboard (EPA ) ECHA InfoCard 100.052.475 Formula C 35 H 62 Br 2 N 4 O 4 Molar mass 762.713 g·mol−1 3D model (JSmol ) show
[Br-].[Br-].O=C(O[C@H]6[C@@H](N1CC[N+](C)(C)CC1)C[C@@H]5[C@]6(C)CC[C@H]3[C@H]5CC[C@H]4C[C@H](OC(=O)C)[C@@H](N2CC[N+](CC2)(C)C)C[C@]34C)C
show
InChI=1S/C35H62N4O4.2BrH/c1-24(40)42-32-21-26-9-10-27-28(35(26,4)23-31(32)37-15-19-39(7,8)20-16-37)11-12-34(3)29(27)22-30(33(34)43-25(2)41)36-13-17-38(5,6)18-14-36;;/h26-33H,9-23H2,1-8H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1
Y Key:TXWBOBJCRVVBJF-YTGGZNJNSA-L
Y
N Y (what is this?)
Pipecuronium (Arduan ) is a bisquaternary aminosteroid muscle relaxant [1] which blocks nicotinic acetylcholine receptors [2] at the neuromuscular junction . It is also an antagonist of M2 and M3 muscarinic receptors [3] and is the most potent neuromuscular blocking agent of the aminosteroid class.[citation needed ]
It is sold under the trade names Arduan and Pycuron. [4]
See also [ ]
References [ ]
show Peripherally acting (primarily antinicotinic ,NMJ block )
Non-depolarizing
Curare alkaloids 4° ammonium agents
Depolarizing ACh release inhibitors
Centrally acting
Directly acting
show nAChRs
Agonists (and PAMs )Antagonists (and NAMs )
Precursors (and prodrugs ) See also: Receptor/signaling modulators • Muscarinic acetylcholine receptor modulators • Acetylcholine metabolism/transport modulators
Categories :
Muscle relaxants Quaternary ammonium compounds Piperazines Acetate esters Bromides Nicotinic antagonists Androstanes Steroid stubs Musculoskeletal system drug stubs Hidden categories:
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