1,3-Dimethylbutylamine
Names
Preferred IUPAC name
Other names
(4-Methylpentan-2-yl)amine
Identifiers
CAS Number
3D model (JSmol )
ChemSpider
ECHA InfoCard
100.003.227
UNII
InChI=1S/C6H15N/c1-5(2)4-6(3)7/h5-6H,4,7H2,1-3H3
Key: UNBMPKNTYKDYCG-UHFFFAOYSA-N
InChI=1/C6H15N/c1-5(2)4-6(3)7/h5-6H,4,7H2,1-3H3
Key: UNBMPKNTYKDYCG-UHFFFAOYAT
Properties
Chemical formula
C 6 H 15 N
Molar mass
101.193 g·mol−1
Density
0.717 g/mL[1]
Boiling point
108–110 °C (226–230 °F; 381–383 K)[1]
Hazards
NFPA 704 (fire diamond)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Chemical compound
1,3-Dimethylbutylamine (1,3-DMBA , dimethylbutylamine , DMBA , 4-amino-2-methylpentane , or AMP ), is a stimulant drug structurally related to methylhexanamine where a butyl group replaces the pentyl group . The compound is an aliphatic amine .
The hydrochloride and citrate salts of DMBA has been identified as unapproved ingredients in some over-the-counter dietary supplements ,[2] [3] [4] in which it is used in an apparent attempt to circumvent bans on methylhexanamine.[5] The U.S. Food and Drug Administration (FDA) considers any dietary supplement containing DMBA to be "adulterated".[6] Despite the FDA's opposition, DMBA continues to be sold in the US.[7]
There are no known human safety studies on DMBA and its health effects are entirely unknown.[2] [3] [8]
References [ ]
^ a b "1,3-Dimethylbutylamine" . Sigma-Aldrich .
^ a b Cohen, Pieter A.; Travis, John C.; Venhuis, Bastiaan J. (2015). "A synthetic stimulant never tested in humans, 1,3-dimethylbutylamine (DMBA), is identified in multiple dietary supplements". Drug Testing and Analysis . 7 (1): 83–7. doi :10.1002/dta.1735 . PMID 25293509 .
^ a b "Unapproved Synthetic Stimulant "DMBA" Found in Multiple Dietary Supplements" . NSF International. Archived from the original on 2016-11-22. Retrieved 2015-03-21 .
^ "FDA Warns 14 Sports Supplement Companies Of Illegal DMBA (AMP Citrate)" . Forbes . May 6, 2015.
^ "Stimulant Potentially Dangerous to Health, FDA Warns" . U.S. Food and Drug Administration. April 11, 2013. Retrieved March 10, 2015 .
^ "DMBA in Dietary Supplements" . Food and Drug Administration .
^ Cohen, Pieter A.; Wen, Anita; Gerona, Roy (1 December 2018). "Prohibited Stimulants in Dietary Supplements After Enforcement Action by the US Food and Drug Administration" . JAMA Internal Medicine . 178 (12): 1721–1723. doi :10.1001/jamainternmed.2018.4846 . PMC 6583602 . PMID 30422217 .
^ "Revealing the hidden dangers of dietary supplements" . Science . 20 August 2015. doi :10.1126/science.aad1651 .
Stimulants
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See also: Receptor/signaling modulators
Dopaminergics
Serotonergics
Monoamine reuptake inhibitors
Monoamine releasing agents
Monoamine metabolism modulators
Monoamine neurotoxins