3',4'-Methylenedioxy-α-pyrrolidinohexiophenone Legal status
UK : Class B
Illegal in Japan and Hungary
1-(2H -1,3-Benzodioxol-5-yl)-2-(pyrrolidin-1-yl)hexan-1-one
CAS Number PubChem CID ChemSpider UNII Formula C 17 H 23 N O 3 Molar mass 289.375 g·mol−1 3D model (JSmol )
CCCCC(C(=O)C1=CC2=C(C=C1)OCO2)N3CCCC3
InChI=1S/C17H23NO3/c1-2-3-6-14(18-9-4-5-10-18)17(19)13-7-8-15-16(11-13)21-12-20-15/h7-8,11,14H,2-6,9-10,12H2,1H3
Key:OBLFRFGUZZRECT-UHFFFAOYSA-N
MDPHP (3',4'-Methylenedioxy-α-pyrrolidinohexiophenone ) is a stimulant of the cathinone class originally developed in the 1960s,[1] which has been reported as a novel designer drug . In the UK its slang name is monkey dust .[2] It is closely related to the potent stimulant MDPV though with slightly milder effects, and has been used as an alternative in some countries following the banning of MDPV.[3] [4] [5] [6]
Legal Status [ ]
MDPHP is specifically listed as a controlled substance in Japan [7] and Hungary,[8] and is controlled under analogue provisions in a number of other jurisdictions.
See also [ ]
References [ ]
^ DE 1545591 , Koeppe H, Zeile K, Ludwig G, "Patent DE - Verfahren zur Herstellung von α-Aminoketonen mit heterocyclischer Aminogruppe", issued 28 May 1965
^ "Monkey Dust drug use 'an epidemic', emergency workers warn" . BBC . 10 August 2018. Retrieved 16 August 2018 .
^ Zaitsu K, Katagi M, Tsuchihashi H, Ishii A (2013). "Recently abused synthetic cathinones, α-pyrrolidinophenone derivatives: A review of their pharmacology, acute toxicity, and metabolism". Forensic Toxicology . 32 : 1–8. doi :10.1007/s11419-013-0218-1 . S2CID 25604845 .
^ Kaizaki-Mitsumoto A, Noguchi N, Yamaguchi S, Odanaka Y, Matsubayashi S, Kumamoto H, et al. (January 2016). "Three 25-NBOMe-type drugs, three other phenethylamine-type drugs (25I-NBMD, RH34, and escaline), eight cathinone derivatives, and a phencyclidine analog MMXE, newly identified in ingredients of drug products before they were sold on the drug market". Forensic Toxicology . 34 (1): 108–14. doi :10.1007/s11419-015-0293-6 . S2CID 45890497 .
^ Beck O, Bäckberg M, Signell P, Helander A (April 2018). "Intoxications in the STRIDA project involving a panorama of psychostimulant pyrovalerone derivatives, MDPV copycats" . Clinical Toxicology . Philadelphia, Pa. 56 (4): 256–263. doi :10.1080/15563650.2017.1370097 . PMID 28895757 . S2CID 3401681 .
^ Fowble KL, Shepard JR, Musah RA (March 2018). "Identification and classification of cathinone unknowns by statistical analysis processing of direct analysis in real time-high resolution mass spectrometry-derived "neutral loss" spectra". Talanta . 179 : 546–553. doi :10.1016/j.talanta.2017.11.020 . PMID 29310273 .
^ "指定薬物名称・構造式一覧(平成27年9月16日現在)" (PDF) (in Japanese). 厚生労働省. 16 September 2015. Retrieved 8 October 2015 .
^ "A Daath.hu kiegészítése a BSZKI "designer jogi listáján" nem szereplő, de a C-lista 1.-4. szerkezeti leírásainak megfelelő, illetve a C-lista 5. felsorolásában szereplő néhány anyagról" [The addition to Daath.hu is not included in the "designer legal list" of the BSZKI, but C-list 1.-4. and some of the substances in list 5 of list C.] (PDF) (in Hungarian).
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SKF-77434
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A-412997
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BP-897
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CP-226,269
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OSU-6162
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PD-128,907
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PF-219,061
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Propylnorapomorphine
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RDS-127
Ro10-5824
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Salvinorin A
SKF-83,959
Sumanirole
Talipexole
Umespirone
WAY-100,635
Antagonists
See also: Receptor/signaling modulators
Adrenergics
Serotonergics
Monoamine reuptake inhibitors
Monoamine releasing agents
Monoamine metabolism modulators
Monoamine neurotoxins