CS-27349
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Formula | C22H25NO3 |
Molar mass | 351.446 g·mol−1 |
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CS-27349, or L-2-α-tropinyl benzilate, is an experimental incapacitating agent. It acts as an antagonist to muscarinic acetylcholine receptors, causing delirium. It has 37% of the potency of the related compound 3-quinuclidinyl benzilate (BZ) in producing peripheral effects, but 85% of the potency in producing central effects. The mean dose required to incapacitate subjects was 1.2 times that of BZ.[1] It has not been in use since the 1970s, and there have been no publications about its effects or long-term toxicology since then.[2]
References[]
- ^ Ball JC (2015). "Dual Use Research of Concern: Derivatives of 3-Quinuclidinyl Benzilate". Military Medical Science Letters. 84 (1): 2–41. doi:10.31482/mmsl.2015.001.
- ^ Assessment of Potential Long-Term Health Effects on Army Human Test Subjects of Relevant Biological and Chemical Agents, Drugs, Medications and Substances (PDF) (Report). Ho-Chunk Technical Solutions Healthcare Division. February 29, 2016.
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Muscarinic acetylcholine receptor modulators | |||||
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See also: Receptor/signaling modulators • Nicotinic acetylcholine receptor modulators • Acetylcholine metabolism/transport modulators |
Retrieved from ""
Categories:
- Muscarinic antagonists
- Deliriants
- Incapacitating agents
- Chemical weapons of the United States
- Benzilate esters
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