EA-3580 show
(1-methylpiperidin-4-yl) 2-cyclobutyl-2-hydroxy-2-phenylacetate
CAS Number PubChem CID ChemSpider CompTox Dashboard (EPA ) Formula C 18 H 25 N O 3 Molar mass 303.402 g·mol−1 3D model (JSmol ) show
c3ccccc3C(O)(C2CCC2)C(=O)OC1CCN(C)CC1
show
InChI=1S/C18H25NO3/c1-19-12-10-16(11-13-19)22-17(20)18(21,15-8-5-9-15)14-6-3-2-4-7-14/h2-4,6-7,15-16,21H,5,8-13H2,1H3
Key:LOBGXFLATZQVKC-UHFFFAOYSA-N
EA-3580 is a potent anticholinergic deliriant drug with a fairly long duration of action, related to the chemical warfare agent 3-Quinuclidinyl benzilate (QNB). It was developed under contract to Edgewood Arsenal during the 1960s as part of the US military chemical weapons program , during research to improve upon the properties of earlier agents such as QNB.
EA-3580 is closely related to the similar compound EA-3443 , and has similar potency and high central to peripheral effects ratio, but with a duration of action around half as long, although effects of EA-3580 can still persist for 24 hours or more following high doses.[1] [2]
See also [ ]
EA-3167
N-methyl-3-piperidyl benzilate
N-ethyl-3-piperidyl benzilate
3-Quinuclidinyl benzilate
Ditran
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See also: Receptor/signaling modulators • Nicotinic acetylcholine receptor modulators • Acetylcholine metabolism/transport modulators