Signaling peptide receptor

Signaling peptide receptor is a type of receptor which binds one or more signaling peptides or signaling proteins.

An example is the tropomyosin receptor kinase B (TrkB), which is bound and activated by the neurotrophic protein brain-derived neurotrophic factor (BDNF). Another example is the μ-opioid receptor (MOR), which is bound and activated by the opioid peptide hormone β-endorphin.

Adiponectin receptor[]

AdipoR₁[]

• Agonists
  • Peptide
    • Adiponectin
  • Non-peptide
    • AdipoRon
    • (–)-Arctigenin
    • Arctiin
    • Gramine
    • Matairesinol
• Antagonists
  • Peptide

AdipoR₂[]

• Agonists
  • Peptide
    • Adiponectin
  • Non-peptide
    • AdipoRon
    • Deoxyschizandrin
    • Parthenolide
    • Taxifoliol
• Antagonists
  • Peptide

Angiotensin receptor[]

Bradykinin receptor[]

• Agonists
  • Bradykinin
  • Kallidin
• Antagonists
  • Icatibant
  • LF22-0542

Calcitonin gene-related peptide receptor[]

• Agonists
  • Amylin
  • CGRP
  • Pramlintide
• Antagonists
  • Atogepant
  • Olcegepant
  • Rimegepant
  • Telcagepant
  • Ubrogepant
• Antibodies
  • Eptinezumab
  • Erenumab
  • Fremanezumab
  • Galcanezumab

Cholecystokinin receptor[]

CCK_A[]

• Agonists
  • Cholecystokinin
• Antagonists
  • Asperlicin
  • Devazepide
  • Dexloxiglumide
  • Lorglumide
  • Proglumide

CCK_B[]

• Agonists
  • Cholecystokinin
  • CCK-4
  • Gastrin
  • Pentagastrin (CCK-5)
• Antagonists
  • CI-988 (PD-134308)
  • Proglumide

Unsorted[]

• Antagonists

Corticotropin-releasing hormone receptor[]

CRF₁[]

• Agonists
  • Corticorelin
  • Corticotropin-releasing hormone
  • Sauvagine
  • Urocortin
• Antagonists
  • Antalarmin
  • Astressin-B
  • CP-154,526
  • Emicerfont
  • Hypericin
  • Pexacerfont
  • Verucerfont

CRF₂[]

• Agonists
  • Corticorelin
  • Corticotropin-releasing hormone
  • Sauvagine
  • Urocortin
• Antagonists
  • Astressin-B

Cytokine receptor[]

Endothelin receptor[]

• Agonists
  • Endothelin 1
  • Endothelin 2
  • Endothelin 3
  • Sarafotoxin
• Antagonists
  • Ambrisentan
  • Atrasentan
  • Bosentan
  • BQ-123
  • BQ-788
  • Clazosentan
  • Darusentan
  • Macitentan
  • Sitaxentan
  • Tezosentan
  • Zibotentan

Galanin receptor[]

GAL₁[]

• Agonists
  • Galanin
  • Galanin-like peptide
  • Galmic
  • Galnon
• Antagonists

GAL₂[]

• Agonists
  • Galanin
  • Galanin-like peptide
  • Galmic
  • Galnon
• Antagonists

GAL₃[]

• Agonists
  • Galanin
  • Galmic
  • Galnon
• Antagonists
  • HT-2157
  • SNAP-37889

Growth hormone secretagogue receptor[]

Growth hormone receptor[]

Growth-hormone-releasing hormone receptor[]

Glucagon-like peptide receptor[]

GLP-1[]

• Agonists
  • Albiglutide
  • Dulaglutide
  • Exenatide
  • GLP-1
  • Liraglutide
  • Lixisenatide
  • Oxyntomodulin
  • Semaglutide
  • Taspoglutide

GLP-2[]

• Agonists
  • GLP-2
  • Teduglutide

Others[]

• Propeptides
  • Preproglucagon
  • Proglucagon

Glucagon receptor[]

• Agonists
  • Dasiglucagon
  • Glucagon
  • Oxyntomodulin
• Antagonists
• Propeptides
  • Preproglucagon
  • Proglucagon

Gonadotropin-releasing hormone receptor[]

Gonadotropin receptor[]

Growth factor receptor[]

Insulin receptor[]

• Agonists
  • Chaetochromin (4548-G05)
  • Insulin-like growth factor 1
  • Insulin-like growth factor 2
  • Insulin
  • Insulin aspart
  • Insulin degludec
  • Insulin detemir
  • Insulin glargine
  • Insulin glulisine
  • Insulin lispro
  • Mecasermin
  • Mecasermin rinfabate
• Antagonists
• Kinase inhibitors
  • Linsitinib
• Antibodies
  • (against IGF-1 and IGF-2)

KiSS1-derived peptide receptor[]

• Agonists
  • Kisspeptin (kisspeptin-54, metastin)
  • MVT-602 (RVT-602, TAK-448)
• Antagonists

Leptin receptor[]

• Agonists
  • Leptin
  • Metreleptin

Melanin-concentrating hormone receptor[]

MCH₁[]

• Agonists
  • Melanin-concentrating hormone
• Antagonists
  • ATC-0175
  • GW-803430
  • NGD-4715
  • SNAP-7941
  • SNAP-94847

MCH₂[]

• Agonists
  • Melanin-concentrating hormone

Melanocortin receptor[]

Neuropeptide FF receptor[]

• Agonists
  • Neuropeptide FF
• Antagonists
  • BIBP-3226

Neuropeptide S receptor[]

• Agonists
  • Neuropeptide S
• Antagonists
  • ML-154
  • SHA-68

Neuropeptide Y receptor[]

Y₁[]

• Agonists
  • Neuropeptide Y
  • Peptide YY
• Antagonists
  • BIBP-3226

Y₂[]

• Agonists
  • Neuropeptide Y
  • Peptide YY
• Antagonists
  • BIIE-0246

Y₄[]

• Agonists
  • Neuropeptide Y
  • Pancreatic polypeptide
  • Peptide YY
• Antagonists
  • UR-AK49

Y₅[]

• Agonists
  • Neuropeptide Y
  • Peptide YY
• Antagonists
  • Lu AA-33810
  • Velneperit (S-2367)

Neurotensin receptor[]

NTS₁[]

• Agonists
  • Neurotensin
  • Neuromedin N
• Antagonists
  • Meclinertant
  • SR-142948

NTS₂[]

• Agonists
  • Neurotensin
• Antagonists
  • Levocabastine
    • SR-142948

Opioid receptor[]

Orexin receptor[]

Oxytocin receptor[]

Prolactin receptor[]

Parathyroid hormone receptor[]

• Agonists
  • Abaloparatide
  • Parathyroid hormone
  • Parathyroid hormone-related protein (PTHrP)
  • Teriparatide

Relaxin receptor[]

• Agonists
  • Insulin-like factor 3
  • Relaxin (, , 3)
  • Serelaxin

Somatostatin receptor[]

Tachykinin receptor[]

Thyrotropin-releasing hormone receptor[]

• Agonists
  • Protirelin
  • Taltirelin
  • TRH (TRF)

Thyrotropin receptor[]

• Agonists
  • Thyrotropin alfa
  • TSH (thyrotropin)

Vasopressin receptor[]

Vasoactive intestinal peptide receptor and Pituitary adenylate cyclase-activating peptide[]

VIPR₁[]

• Agonists
  • Peptide
    • PACAP
    • VIP

VIPR₂[]

• Agonists
  • Peptide
    • LBT-3627
    • PACAP
    • VIP

PAC₁[]

• Agonists
  • PACAP
• Antagonists

Unsorted[]

Others[]

• Endogenous
  • Adrenomedullin
  • Apelin
  • Asprosin
  • Bombesin
  • Calcitonin
  • Carnosine
  • CART
  • CLIP
  • DSIP
  • Enteroglucagon
  • Formyl peptide
  • GALP
  • GIP
  • GRP
  • Integrin ligands
    • collagens
    • fibrinogen
    • fibronectin
    • laminins
    • ICAM-1
    • ICAM-2
    • osteopontin
    • VCAM-1
    • vitronectin
  • Kininogens
  • Motilin
  • Natriuretic peptides
    • ANP
    • BNP
    • CNP
    • urodilatin
  • Nesfatin-1
  • Neuromedin B
  • Neuromedin N
  • Neuromedin S
  • Neuromedin U
  • Obestatin
  • Osteocalcin
  • Resistin
  • Secretin
  • Thymopoietin
  • Thymosins
  • Thymulin
  • Urotensin-II
  • VGF
• Exogenous
  • Lifitegrast (LFA-1 antagonist)

See also[]

• Neuropeptide receptor
• Neurotransmitter receptor

References[]

External links[]

• Peptide+receptor at the US National Library of Medicine Medical Subject Headings (MeSH)