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MRGPRX3 Identifiers Aliases MRGPRX3 , GPCR, MRGX3, SNSR1, SNSR2, MAS related GPR family member X3External IDs OMIM : 607229 MGI : 3033148 HomoloGene : 79615 GeneCards : MRGPRX3 Gene location (Human ) Chr. Chromosome 11 (human) [1] Band 11p15.1 Start 18,120,955 bp [1] End 18,138,488 bp [1]
Gene location (Mouse ) Chr. Chromosome 7 (mouse)[2] Band 7|7 B3 Start 46,884,609 bp [2] End 46,902,596 bp [2]
Gene ontology Molecular function Cellular component Biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 11: 18.12 – 18.14 Mb Chr 7: 46.88 – 46.9 Mb PubMed search[3] [4] Wikidata
Mas-related G-protein coupled receptor member X3 is a protein that in humans is encoded by the MRGPRX3 gene .[5] [6]
See also [ ]
References [ ]
Further reading [ ]
Lembo PM, Grazzini E, Groblewski T, et al. (2002). "Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs". Nat. Neurosci . 5 (3): 201–9. doi :10.1038/nn815 . PMID 11850634 . S2CID 42544746 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 . PMID 15489334 .
Kaisho Y, Watanabe T, Nakata M, et al. (2005). "Transgenic rats overexpressing the human MrgX3 gene show cataracts and an abnormal skin phenotype". Biochem. Biophys. Res. Commun . 330 (3): 653–7. doi :10.1016/j.bbrc.2005.03.027 . PMID 15809047 .
Cell surface receptor : G protein-coupled receptors
Neurotransmitter
Adrenergic
α1 (A
B
D )
α2 (A
B
C )
β1
β2
β3
Purinergic
Adenosine (A1
A2A
A2B
A3 )
P2Y (1
2
4
5
6
8
9
10
11
12
13
14 )
Serotonin Other
Acetylcholine (M1
M2
M3
M4
M5 )
Dopamine
GHB receptor
Histamine
Melatonin (1A
1B
1C )
TAAR (1
2
5
6
8
9 )
Metabolites and signaling molecules
Eicosanoid
CysLT (1
2 )
LTB4
FPRL1
OXE
Prostaglandin
DP (1
2 ), EP (1
2
3
4 ), FP
Prostacyclin
Thromboxane
Other
Peptide
Miscellaneous
Taste , sweetOther
Calcium-sensing receptor
GABAB (1
2 )
Glutamate receptor (Metabotropic glutamate (1
2
3
4
5
6
7
8 ))
GPRC6A
GPR (156
158
179 )
RAIG (1
2
3
4 )
Categories :
Genes on human chromosome 11 G protein-coupled receptors Transmembrane receptor stubs