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ADGRA3 Identifiers Aliases ADGRA3 , PGR21, TEM5L, GPR125, adhesion G protein-coupled receptor A3External IDs OMIM : 612303 MGI : 1917943 HomoloGene : 19235 GeneCards : ADGRA3 Gene location (Human ) Chr. Chromosome 4 (human) [1] Band 4p15.2 Start 22,345,071 bp [1] End 22,516,066 bp [1]
Gene location (Mouse ) Chr. Chromosome 5 (mouse)[2] Band 5|5 B3 Start 50,117,298 bp [2] End 50,216,348 bp [2]
Gene ontology Molecular function Cellular component Biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 4: 22.35 – 22.52 Mb Chr 5: 50.12 – 50.22 Mb PubMed search[3] [4] Wikidata
Probable G-protein coupled receptor 125 is a protein that in humans is encoded by the GPR125 gene .[5] [6]
References [ ]
Further reading [ ]
Seandel M; et al. (2007). "Generation of functional multipotent adult stem cells from GPR125+ germline progenitors" . Nature . 449 (7160): 346–50. Bibcode :2007Natur.449..346S . doi :10.1038/nature06129 . PMC 2935199 . PMID 17882221 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment" . Genome Res . 13 (10): 2265–70. doi :10.1101/gr.1293003 . PMC 403697 . PMID 12975309 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 . PMID 14702039 .
Yamamoto Y, Irie K, Asada M, et al. (2004). "Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein" . Oncogene . 23 (22): 3889–97. doi :10.1038/sj.onc.1207495 . PMID 15021905 .
Bjarnadóttir TK, Fredriksson R, Höglund PJ, et al. (2005). "The human and mouse repertoire of the adhesion family of G-protein-coupled receptors". Genomics . 84 (1): 23–33. doi :10.1016/j.ygeno.2003.12.004 . PMID 15203201 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 . PMID 15489334 .
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635–48. doi :10.1016/j.cell.2006.09.026 . PMID 17081983 . S2CID 7827573 .
Cell surface receptor : G protein-coupled receptors
Neurotransmitter
Adrenergic
α1 (A
B
D )
α2 (A
B
C )
β1
β2
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2
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10
11
12
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158
179 )
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Categories :
Genes on human chromosome 4 G protein-coupled receptors Transmembrane receptor stubs