From Wikipedia, the free encyclopedia
NMUR1 Identifiers Aliases NMUR1 , (FM-3), FM-3, FM3, GPC-R, GPR66, NMU1R, Neuromedin U receptor 1External IDs OMIM : 604153 MGI : 1341898 HomoloGene : 68501 GeneCards : NMUR1 Gene location (Human ) Chr. Chromosome 2 (human) [1] Band 2q37.1 Start 231,523,187 bp [1] End 231,530,445 bp [1]
Gene location (Mouse ) Chr. Chromosome 1 (mouse)[2] Band 1|1 C5 Start 86,314,025 bp [2] End 86,353,950 bp [2]
Gene ontology Molecular function Cellular component Biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 2: 231.52 – 231.53 Mb Chr 1: 86.31 – 86.35 Mb PubMed search[3] [4] Wikidata
Neuromedin-U receptor 1 is a protein that in humans is encoded by the NMUR1 gene .[5] [6]
See also [ ]
References [ ]
^ a b c GRCh38: Ensembl release 89: ENSG00000171596 - Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026237 - Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Tan CP, McKee KK, Liu Q, Palyha OC, Feighner SD, Hreniuk DL, Smith RG, Howard AD (Dec 1998). "Cloning and characterization of a human and murine T-cell orphan G-protein-coupled receptor similar to the growth hormone secretagogue and neurotensin receptors". Genomics . 52 (2): 223–9. doi :10.1006/geno.1998.5441 . PMID 9782091 .
^ "Entrez Gene: NMUR1 neuromedin U receptor 1" .
Further reading [ ]
Fujii R, Hosoya M, Fukusumi S, et al. (2000). "Identification of neuromedin U as the cognate ligand of the orphan G protein-coupled receptor FM-3" . J. Biol. Chem . 275 (28): 21068–74. doi :10.1074/jbc.M001546200 . PMID 10783389 .
Szekeres PG, Muir AI, Spinage LD, et al. (2000). "Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3" . J. Biol. Chem . 275 (27): 20247–50. doi :10.1074/jbc.C000244200 . PMID 10811630 .
Raddatz R, Wilson AE, Artymyshyn R, et al. (2000). "Identification and characterization of two neuromedin U receptors differentially expressed in peripheral tissues and the central nervous system" . J. Biol. Chem . 275 (42): 32452–9. doi :10.1074/jbc.M004613200 . PMID 10899166 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 . PMID 15489334 .
Mori K, Miyazato M, Ida T, et al. (2005). "Identification of neuromedin S and its possible role in the mammalian circadian oscillator system" . EMBO J . 24 (2): 325–35. doi :10.1038/sj.emboj.7600526 . PMC 545815 . PMID 15635449 .
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4" . Nature . 434 (7034): 724–31. doi :10.1038/nature03466 . PMID 15815621 .
External links [ ]
"Neuromedin U Receptors: NMU1" . IUPHAR Database of Receptors and Ion Channels . International Union of Basic and Clinical Pharmacology.
NMUR1 human gene location in the UCSC Genome Browser .
NMUR1 human gene details in the UCSC Genome Browser .
Cell surface receptor : G protein-coupled receptors
Neurotransmitter
Adrenergic
α1 (A
B
D )
α2 (A
B
C )
β1
β2
β3
Purinergic
Adenosine (A1
A2A
A2B
A3 )
P2Y (1
2
4
5
6
8
9
10
11
12
13
14 )
Serotonin Other
Acetylcholine (M1
M2
M3
M4
M5 )
Dopamine
GHB receptor
Histamine
Melatonin (1A
1B
1C )
TAAR (1
2
5
6
8
9 )
Metabolites and signaling molecules
Eicosanoid
CysLT (1
2 )
LTB4
FPRL1
OXE
Prostaglandin
DP (1
2 ), EP (1
2
3
4 ), FP
Prostacyclin
Thromboxane
Other
Peptide
Miscellaneous
Taste , sweetOther
Calcium-sensing receptor
GABAB (1
2 )
Glutamate receptor (Metabotropic glutamate (1
2
3
4
5
6
7
8 ))
GPRC6A
GPR (156
158
179 )
RAIG (1
2
3
4 )
Categories :
Genes on human chromosome 2 G protein-coupled receptors Transmembrane receptor stubs