Glucagon receptor family

From Wikipedia, the free encyclopedia

The glucagon receptor family[1] is a group of closely related G-protein coupled receptors which include:

  • Glucagon receptor
  • Glucagon-like peptide 1 receptor
  • Glucagon-like peptide 2 receptor
  • Gastric inhibitory polypeptide receptor

The first three receptors bind closely related peptide hormones (glucagon, glucagon-like peptide-1, glucagon-like peptide-2) derived from the proglucagon polypeptide. The last receptor binds gastric inhibitory polypeptide.

References[]

  1. ^ Brubaker PL, Drucker DJ (2002). "Structure-function of the glucagon receptor family of G protein-coupled receptors: the glucagon, GIP, GLP-1, and GLP-2 receptors" (PDF). Recept. Channels. 8 (3–4): 179–88. doi:10.1080/10606820213687. PMID 12529935. Retrieved 2008-07-14.

External links[]

  • "Glucagon Receptors". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived from the original on 2018-01-25.
Retrieved from ""