From Wikipedia, the free encyclopedia
TAS2R39 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | TAS2R39, T2R39, T2R57, taste 2 receptor member 39 |
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External IDs | MGI: 2681308 HomoloGene: 52214 GeneCards: TAS2R39 |
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Gene location (Human) |
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![Chromosome 7 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/9/99/Ideogram_human_chromosome_7.svg/300px-Ideogram_human_chromosome_7.svg.png) | Chr. | Chromosome 7 (human)[1] |
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| Band | 7q34 | Start | 143,183,419 bp[1] |
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End | 143,184,435 bp[1] |
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Gene location (Mouse) |
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![Chromosome 6 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Ideogram_house_mouse_chromosome_6.svg/260px-Ideogram_house_mouse_chromosome_6.svg.png) | Chr. | Chromosome 6 (mouse)[2] |
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| Band | 6|6 B2.1 | Start | 42,140,936 bp[2] |
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End | 42,141,895 bp[2] |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 7: 143.18 – 143.18 Mb | Chr 6: 42.14 – 42.14 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
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Taste receptor type 2 member 39 is a protein that in humans is encoded by the TAS2R39 gene.[5][6]
See also[]
References[]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000236398 - Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000047102 - Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855. S2CID 20426192.
- ^ "Entrez Gene: TAS2R39 taste receptor, type 2, member 39".
Further reading[]
- Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
- Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982. S2CID 37807140.
- Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520. S2CID 718601.
- Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.
- Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Cell surface receptor: G protein-coupled receptors |
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Neurotransmitter | Adrenergic |
- α1 (A
- B
- D)
- α2 (A
- B
- C)
- β1
- β2
- β3
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Purinergic |
- Adenosine (A1
- A2A
- A2B
- A3)
- P2Y (1
- 2
- 4
- 5
- 6
- 8
- 9
- 10
- 11
- 12
- 13
- 14)
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Serotonin | |
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Other |
- Acetylcholine (M1
- M2
- M3
- M4
- M5)
- Dopamine
- GHB receptor
- Histamine
- Melatonin (1A
- 1B
- 1C)
- TAAR (1
- 2
- 5
- 6
- 8
- 9)
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Metabolites and signaling molecules | Eicosanoid |
- CysLT (1
- 2)
- LTB4
- FPRL1
- OXE
- Prostaglandin
- DP (1
- 2), EP (1
- 2
- 3
- 4), FP
- Prostacyclin
- Thromboxane
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Other | |
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Peptide | |
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Miscellaneous | |
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Taste, sweet | |
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Other |
- Calcium-sensing receptor
- GABAB (1
- 2)
- Glutamate receptor (Metabotropic glutamate (1
- 2
- 3
- 4
- 5
- 6
- 7
- 8))
- GPRC6A
- GPR (156
- 158
- 179)
- RAIG (1
- 2
- 3
- 4)
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Categories:
- Genes on human chromosome 7
- Human taste receptors
- Transmembrane receptor stubs
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