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PROKR1 Identifiers Aliases PROKR1 , GPR73, GPR73a, PKR1, ZAQ, prokineticin receptor 1, PK-R1External IDs OMIM : 607122 MGI : 1929676 HomoloGene : 10968 GeneCards : PROKR1 Gene location (Human ) Chr. Chromosome 2 (human) [1] Band 2p13.3 Start 68,643,579 bp [1] End 68,658,251 bp [1]
Gene location (Mouse ) Chr. Chromosome 6 (mouse)[2] Band 6|6 D1 Start 87,555,573 bp [2] End 87,567,725 bp [2]
Gene ontology Molecular function Cellular component Biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 2: 68.64 – 68.66 Mb Chr 6: 87.56 – 87.57 Mb PubMed search[3] [4] Wikidata
Prokineticin receptor 1 , also known as PKR1 , is a human protein encoded by the PROKR1 gene .[5]
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References [ ]
Further reading [ ]
Parker R, Liu M, Eyre HJ, et al. (2000). "Y-receptor-like genes GPR72 and GPR73: molecular cloning, genomic organisation and assignment to human chromosome 11q21.1 and 2p14 and mouse chromosome 9 and 6". Biochim. Biophys. Acta . 1491 (1–3): 369–75. doi :10.1016/s0167-4781(00)00023-3 . PMID 10760605 .
Lin DC, Bullock CM, Ehlert FJ, et al. (2002). "Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor" . J. Biol. Chem . 277 (22): 19276–80. doi :10.1074/jbc.M202139200 . PMID 11886876 .
Masuda Y, Takatsu Y, Terao Y, et al. (2002). "Isolation and identification of EG-VEGF/prokineticins as cognate ligands for two orphan G-protein-coupled receptors". Biochem. Biophys. Res. Commun . 293 (1): 396–402. doi :10.1016/S0006-291X(02)00239-5 . PMID 12054613 .
Soga T, Matsumoto S, Oda T, et al. (2003). "Molecular cloning and characterization of prokineticin receptors". Biochim. Biophys. Acta . 1579 (2–3): 173–9. doi :10.1016/S0167-4781(02)00546-8 . PMID 12427552 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 . PMID 14702039 .
Battersby S, Critchley HO, Morgan K, et al. (2004). "Expression and regulation of the prokineticins (endocrine gland-derived vascular endothelial growth factor and Bv8) and their receptors in the human endometrium across the menstrual cycle" . J. Clin. Endocrinol. Metab . 89 (5): 2463–9. doi :10.1210/jc.2003-032012 . PMID 15126578 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 . PMID 15489334 .
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4" . Nature . 434 (7034): 724–31. Bibcode :2005Natur.434..724H . doi :10.1038/nature03466 . PMID 15815621 .
Pasquali D, Rossi V, Staibano S, et al. (2006). "The endocrine-gland-derived vascular endothelial growth factor (EG-VEGF)/prokineticin 1 and 2 and receptor expression in human prostate: Up-regulation of EG-VEGF/prokineticin 1 with malignancy" . Endocrinology . 147 (9): 4245–51. doi :10.1210/en.2006-0614 . PMID 16763065 .
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Genes on human chromosome 2 Transmembrane receptor stubs G protein-coupled receptors