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TAS2R43 Identifiers Aliases TAS2R43 , T2R43, T2R52, taste 2 receptor member 43External IDs OMIM : 612668 HomoloGene : 128798 GeneCards : TAS2R43 Gene location (Human ) Chr. Chromosome 12 (human) [1] Band 12p13.2 Start 11,091,287 bp [1] End 11,092,313 bp [1]
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 12: 11.09 – 11.09 Mb n/a PubMed search[2] n/a Wikidata
Taste receptor type 2 member 43 is a protein that in humans is encoded by the TAS2R43 gene .[3] [4]
See also [ ]
References [ ]
^ a b c ENSG00000262612, ENSG00000282537 GRCh38: Ensembl release 89: ENSG00000255374, ENSG00000262612, ENSG00000282537 - Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet . 32 (3): 397–401. doi :10.1038/ng1014 . PMID 12379855 . S2CID 20426192 .
^ "Entrez Gene: TAS2R43 taste receptor, type 2, member 43" .
Further reading [ ]
Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction" . J. Biol. Chem . 277 (1): 1–4. doi :10.1074/jbc.R100054200 . PMID 11696554 .
Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol . 12 (4): 366–71. doi :10.1016/S0959-4388(02)00345-8 . PMID 12139982 . S2CID 37807140 .
Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways" . Cell . 112 (3): 293–301. doi :10.1016/S0092-8674(03)00071-0 . PMID 12581520 . S2CID 718601 .
Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ (2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family". Cytogenet. Genome Res . 98 (1): 45–53. doi :10.1159/000068546 . PMID 12584440 . S2CID 1542970 .
Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes" . Mol. Biol. Evol . 22 (3): 432–6. doi :10.1093/molbev/msi027 . PMID 15496549 .
Kuhn C, Bufe B, Winnig M, Hofmann T, Frank O, Behrens M, Lewtschenko T, Slack JP, Ward CD, Meyerhof W (2005). "Bitter taste receptors for saccharin and acesulfame K." J. Neurosci . 24 (45): 10260–5. doi :10.1523/JNEUROSCI.1225-04.2004 . PMC 6730199 . PMID 15537898 .
Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates" . Genetics . 170 (1): 313–26. doi :10.1534/genetics.104.037523 . PMC 1449719 . PMID 15744053 .
Behrens M, Bartelt J, Reichling C, Winnig M, Kuhn C, Meyerhof W (2006). "Members of RTP and REEP gene families influence functional bitter taste receptor expression" . J. Biol. Chem . 281 (29): 20650–9. doi :10.1074/jbc.M513637200 . PMID 16720576 .
This article incorporates text from the United States National Library of Medicine , which is in the public domain .
Cell surface receptor : G protein-coupled receptors
Neurotransmitter
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α2 (A
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Serotonin Other
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