CLCA4

From Wikipedia, the free encyclopedia
CLCA4
Identifiers
AliasesCLCA4, CaCC, CaCC2, chloride channel accessory 4
External IDsOMIM: 616857 MGI: 2139744 HomoloGene: 40808 GeneCards: CLCA4
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_012128

NM_207208

RefSeq (protein)

NP_036260

NP_997091

Location (UCSC)Chr 1: 86.55 – 86.58 MbChr 3: 144.66 – 144.68 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Chloride channel accessory 4, also known as CLCA4, is a protein which in humans CLCA4 gene. The protein encoded by this gene is a chloride channel.[5] Protein structure prediction methods suggest the N-terminal region of CLCA4 protein is a zinc metalloprotease, and the protein is not an ion channel per se.[6]

See also[]

  • Chloride channel

References[]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000016602 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000068547 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Agnel M, Vermat T, Culouscou JM (July 1999). "Identification of three novel members of the calcium-dependent chloride channel (CaCC) family predominantly expressed in the digestive tract and trachea". FEBS Lett. 455 (3): 295–301. doi:10.1016/S0014-5793(99)00891-1. PMID 10437792. S2CID 82094058.
  6. ^ Pawłowski K, Lepistö M, Meinander N, et al. (2006). "Novel conserved hydrolase domain in the CLCA family of alleged calcium-activated chloride channels". Proteins. 63 (3): 424–39. doi:10.1002/prot.20887. PMID 16470849. S2CID 40041491.

Further reading[]

External links[]

  • CLCA3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
  • Human CLCA4 genome location and CLCA4 gene details page in the UCSC Genome Browser.


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