GJB7

GJB7
Identifiers
Aliases	GJB7, CX25, bA136M9.1, connexin25, gap junction protein beta 7
External IDs	OMIM: 611921 HomoloGene: 89311 GeneCards: GJB7
Gene location (Human)
Chr.	Chromosome 6 (human)
End	87,329,278 bp
Gene ontology
Molecular function	• gap junction channel activity;
Cellular component	• integral component of membrane; • gap junction; • cell junction; • plasma membrane; • connexin complex; • membrane;
Biological process	• cell communication; • transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	375519
	n/a
	ENSG00000164411
	n/a
	Q6PEY0
	n/a
	NM_198568
	n/a
	NP_940970
	n/a
	Wikidata
View/Edit Human

Gap junction beta-7 protein (GJB7), also known as connexin-25 (Cx25), is a protein that in humans is encoded by the GJB7 gene.^[3]

Function[]

Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.^[3]^[4]

References[]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000164411 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: gap junction protein".
^ Söhl G, Nielsen PA, Eiberger J, Willecke K (2003). "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues". Cell Commun. Adhes. 10 (1): 27–36. doi:10.1080/15419060302063. PMID 12881038. S2CID 225894.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000164411 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-3] "Entrez Gene: gap junction protein".

[pmid12881038-4] Söhl G, Nielsen PA, Eiberger J, Willecke K (2003). "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues". Cell Commun. Adhes. 10 (1): 27–36. doi:10.1080/15419060302063. PMID 12881038. S2CID 225894.

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