CLIC3

CLIC3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3FY7, 3KJY
Identifiers
Aliases	CLIC3, chloride intracellular channel 3
External IDs	OMIM: 606533 MGI: 1916704 HomoloGene: 3432 GeneCards: CLIC3
Gene location (Human)
Chr.	Chromosome 9 (human)
End	136,996,568 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	25,348,788 bp
RNA expression pattern
	Top expressed in
	thyroid gland; ; cavity of mouth; ; gums;
	More reference expression data
	n/a
Gene ontology
Molecular function	GO:0001948 protein binding; voltage-gated ion channel activity; chloride channel activity; glutathione transferase activity;
Cellular component	cytoplasm; integral component of membrane; extracellular exosome; membrane; nucleus; chloride channel complex; nuclear body;
Biological process	regulation of ion transmembrane transport; chloride transport; ion transport; signal transduction; chloride transmembrane transport; glutathione metabolic process; transport; ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	9022
	69454
	ENSG00000169583
	ENSMUSG00000015093
	O95833
	Q9D7P7
	NM_004669
	NM_027085
	NP_004660
	NP_081361
	Wikidata
View/Edit Human	View/Edit Mouse

Chloride intracellular channel protein 3 is a protein that in humans is encoded by the CLIC3 gene.^[5] This protein is a chloride channel.^[5]

References[]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000169583 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000015093 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Qian Z, Okuhara D, Abe MK, Rosner MR (Feb 1999). "Molecular cloning and characterization of a mitogen-activated protein kinase-associated intracellular chloride channel". J Biol Chem. 274 (3): 1621–7. doi:10.1074/jbc.274.3.1621. PMID 9880541.

CLIC3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
Human CLIC3 genome location and CLIC3 gene details page in the UCSC Genome Browser.
Overview of all the structural information available in the PDB for UniProt: O95833 (Human Chloride intracellular channel protein 3 (CLIC3)) at the PDBe-KB.

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