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KCNS2 Identifiers Aliases KCNS2 , KV9.2, potassium voltage-gated channel modifier subfamily S member 2External IDs OMIM : 602906 MGI : 1197011 HomoloGene : 22465 GeneCards : KCNS2 Gene location (Human ) Chr. Chromosome 8 (human) [1] Band 8q22.2 Start 98,426,958 bp [1] End 98,432,853 bp [1]
Gene location (Mouse ) Chr. Chromosome 15 (mouse)[2] Band 15|15 B3.1 Start 34,837,501 bp [2] End 34,843,553 bp [2]
Gene ontology Molecular function Cellular component Biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 8: 98.43 – 98.43 Mb Chr 15: 34.84 – 34.84 Mb PubMed search[3] [4] Wikidata
Potassium voltage-gated channel subfamily S member 2 is a protein that in humans is encoded by the KCNS2 gene .[5] [6] The protein encoded by this gene is a voltage-gated potassium channel subunit.[5] [6]
References [ ]
^ a b c GRCh38: Ensembl release 89: ENSG00000156486 - Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000050963 - Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ a b Salinas M, Duprat F, Heurteaux C, Hugnot JP, Lazdunski M (Oct 1997). "New modulatory alpha subunits for mammalian Shab K+ channels" . J Biol Chem . 272 (39): 24371–9. doi :10.1074/jbc.272.39.24371 . PMID 9305895 .
^ a b Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev . 57 (4): 473–508. doi :10.1124/pr.57.4.10 . PMID 16382104 . S2CID 219195192 .
Further reading [ ]
Banfi S, Borsani G, Rossi E, et al. (1996). "Identification and mapping of human cDNAs homologous to Drosophila mutant genes through EST database searching". Nat. Genet . 13 (2): 167–74. doi :10.1038/ng0696-167 . PMID 8640222 . S2CID 38441640 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
Hirosawa M, Nagase T, Ishikawa K, et al. (1999). "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain" . DNA Res . 6 (5): 329–36. doi :10.1093/dnares/6.5.329 . PMID 10574461 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 . PMID 15489334 .
External links [ ]
Ligand-gated Voltage-gated
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β-subunits
γ-subunits
Na+ : Sodium channel
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Epithelial sodium channel
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Amiloride-sensitive cation channel
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K+ : Potassium channel
Calcium-activated Inward-rectifier Tandem pore domain Voltage-gated
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Cl− : Chloride channel
Calcium-activated chloride channels
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Chloride Channel Accessory
CFTR
CLCN
CLIC
CLNS
H+ : Proton channel M+ : CNG cation channel M+ : TRP cation channel H2 O (+ solutes ): Porin Cytoplasm : Gap junction
see also disorders
Categories :
Genes on human chromosome 8 Ion channels Membrane protein stubs