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KCNH6 Identifiers Aliases KCNH6 , ERG-2, ERG2, HERG2, Kv11.2, hERG-2, potassium voltage-gated channel subfamily H member 6External IDs OMIM : 608168 MGI : 2684139 HomoloGene : 32740 GeneCards : KCNH6 Gene location (Human ) Chr. Chromosome 17 (human) [1] Band 17q23.3 Start 63,523,334 bp [1] End 63,548,977 bp [1]
Gene location (Mouse ) Chr. Chromosome 11 (mouse)[2] Band 11|11 E1 Start 106,008,124 bp [2] End 106,034,549 bp [2]
Gene ontology Molecular function Cellular component Biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 17: 63.52 – 63.55 Mb Chr 11: 106.01 – 106.03 Mb PubMed search[3] [4] Wikidata
Potassium voltage-gated channel subfamily H member 6 is a protein that in humans is encoded by the KCNH6 gene .[5] The protein encoded by this gene is a voltage-gated potassium channel subunit.[5]
References [ ]
^ a b c GRCh38: Ensembl release 89: ENSG00000173826 - Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000001901 - Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ a b Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev . 57 (4): 473–508. doi :10.1124/pr.57.4.10 . PMID 16382104 . S2CID 219195192 .
Further reading [ ]
Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
Ganetzky B, Robertson GA, Wilson GF, et al. (1999). "The eag family of K+ channels in Drosophila and mammals". Ann. N. Y. Acad. Sci . 868 (1): 356–69. Bibcode :1999NYASA.868..356G . doi :10.1111/j.1749-6632.1999.tb11297.x . PMID 10414305 . S2CID 33512855 .
Bauer CK, Wulfsen I, Schäfer R, et al. (2003). "HERG K(+) currents in human prolactin-secreting adenoma cells". Pflügers Arch . 445 (5): 589–600. doi :10.1007/s00424-002-0980-0 . PMID 12634931 . S2CID 20178757 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 . PMID 15489334 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 . PMID 14702039 .
External links [ ]
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H+ : Proton channel M+ : CNG cation channel M+ : TRP cation channel H2 O (+ solutes ): Porin Cytoplasm : Gap junction
see also disorders
Categories :
Genes on human chromosome 17 Ion channels Membrane protein stubs