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KCNS1 Identifiers Aliases KCNS1 External IDs OMIM : 602905 MGI : 1197019 HomoloGene : 20517 GeneCards : KCNS1 Gene location (Human ) Chr. Chromosome 20 (human) [1] Band 20q13.12 Start 45,091,214 bp [1] End 45,101,127 bp [1]
Gene location (Mouse ) Chr. Chromosome 2 (mouse)[2] Band 2|2 H3 Start 164,005,539 bp [2] End 164,013,033 bp [2]
Gene ontology Molecular function Cellular component Biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 20: 45.09 – 45.1 Mb Chr 2: 164.01 – 164.01 Mb PubMed search[3] [4] Wikidata
Potassium voltage-gated channel subfamily S member 1 is a protein that in humans is encoded by the KCNS1 gene .[5] [6] protein encoded by this gene is a voltage-gated potassium channel subunit.[5] [6]
References [ ]
^ a b c GRCh38: Ensembl release 89: ENSG00000124134 - Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040164 - Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ a b Salinas M, Duprat F, Heurteaux C, Hugnot JP, Lazdunski M (Oct 1997). "New modulatory alpha subunits for mammalian Shab K+ channels" . J Biol Chem . 272 (39): 24371–9. doi :10.1074/jbc.272.39.24371 PMID 9305895 . ^ a b Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev . 57 (4): 473–508. doi :10.1124/pr.57.4.10 . PMID 16382104 . S2CID 219195192 .
Further reading [ ]
Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Shepard AR, Rae JL (1999). "Electrically silent potassium channel subunits from human lens epithelium". Am. J. Physiol . 277 (3 Pt 1): C412–24. doi :10.1152/ajpcell.1999.277.3.C412 . PMID 10484328 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Fossey SC, Mychaleckyj JC, Pendleton JK, et al. (2001). "A high-resolution 6.0-megabase transcript map of the type 2 diabetes susceptibility region on human chromosome 20". Genomics . 76 (1–3): 45–57. doi :10.1006/geno.2001.6584 . PMID 11549316 . Deloukas P, Matthews LH, Ashurst J, et al. (2001). "The DNA sequence and comparative analysis of human chromosome 20" . Nature . 414 (6866): 865–71. Bibcode :2001Natur.414..865D . doi :10.1038/414865a PMID 11780052 .
External links [ ]
Ligand-gated Voltage-gated
α2 δ-subunits
β-subunits
γ-subunits
Na+ : Sodium channel
Constitutively active
Epithelial sodium channel
Proton -gated
Amiloride-sensitive cation channel
Voltage-gated
Nav α
1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 7A Nav β
K+ : Potassium channel
Calcium-activated Inward-rectifier Tandem pore domain Voltage-gated
Miscellaneous
Cl− :Chloride channel
Calcium-activated chloride channels
Anoctamin
Bestrophin
Chloride Channel Accessory
CFTR CLCN
CLIC
CLNS
H+ :Proton channel M+ :CNG cation channel M+ :TRP cation channel H2 O (+ solutes ):Porin Cytoplasm :Gap junction
see also disorders
Categories :
Genes on human chromosome 20 Ion channels Membrane protein stubs
