KCNK15

KCNK15
Identifiers
Aliases	KCNK15, K2p15.1, KCNK11, KCNK14, KT3.3, TASK-5, TASK5, dJ781B1.1, potassium two pore domain channel subfamily K member 15
External IDs	OMIM: 607368 MGI: 2675209 HomoloGene: 11179 GeneCards: KCNK15
Gene location (Human)
Chr.	Chromosome 20 (human)
End	44,752,313 bp
Gene ontology
Molecular function	• voltage-gated ion channel activity; • potassium channel activity; • potassium ion leak channel activity;
Cellular component	• integral component of membrane; • plasma membrane; • membrane; • integral component of plasma membrane;
Biological process	• potassium ion transport; • regulation of ion transmembrane transport; • cardiac conduction; • ion transport; • stabilization of membrane potential; • potassium ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	60598
	241769
	ENSG00000124249
	ENSMUSG00000035238
	Q9H427
	n/a
	NM_022358
	NM_001030292
	NP_071753
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium channel subfamily K member 15 is a protein that in humans is encoded by the KCNK15 gene.^[4]^[5]^[6]^[7]

This gene encodes K_2P15.1, one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. K_2P15.1 has not been shown to be a functional channel; however, it may require other non-pore-forming proteins for activity.^[7]

References[]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000124249 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kim D, Gnatenco C (Jun 2001). "TASK-5, a new member of the tandem-pore K(+) channel family". Biochem Biophys Res Commun. 284 (4): 923–30. doi:10.1006/bbrc.2001.5064. PMID 11409881.
^ Vega-Saenz de Miera E, Lau DH, Zhadina M, Pountney D, Coetzee WA, Rudy B (Jun 2001). "KT3.2 and KT3.3, two novel human two-pore K(+) channels closely related to TASK-1". J Neurophysiol. 86 (1): 130–42. doi:10.1152/jn.2001.86.1.130. PMID 11431495.
^ Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (Dec 2005). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels". Pharmacol Rev. 57 (4): 527–40. doi:10.1124/pr.57.4.12. PMID 16382106. S2CID 7356601.
^ ^a ^b "Entrez Gene: KCNK15 potassium channel, subfamily K, member 15".

External links[]

KCNK15+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000124249 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11409881-4] Kim D, Gnatenco C (Jun 2001). "TASK-5, a new member of the tandem-pore K(+) channel family". Biochem Biophys Res Commun. 284 (4): 923–30. doi:10.1006/bbrc.2001.5064. PMID 11409881.

[pmid11431495-5] Vega-Saenz de Miera E, Lau DH, Zhadina M, Pountney D, Coetzee WA, Rudy B (Jun 2001). "KT3.2 and KT3.3, two novel human two-pore K(+) channels closely related to TASK-1". J Neurophysiol. 86 (1): 130–42. doi:10.1152/jn.2001.86.1.130. PMID 11431495.

[pmid16382106-6] Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (Dec 2005). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels". Pharmacol Rev. 57 (4): 527–40. doi:10.1124/pr.57.4.12. PMID 16382106. S2CID 7356601.

[entrez-7] "Entrez Gene: KCNK15 potassium channel, subfamily K, member 15".

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KCNK15

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