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KCNG3 Identifiers Aliases KCNG3 External IDs OMIM : 606767 MGI : 2663923 HomoloGene : 15168 GeneCards : KCNG3 Gene location (Human ) Chr. Chromosome 2 (human) [1] Band 2p21 Start 42,442,017 bp [1] End 42,493,982 bp [1]
Gene location (Mouse ) Chr. Chromosome 17 (mouse)[2] Band 17|17 E4 Start 83,893,386 bp [2] End 83,939,324 bp [2]
Gene ontology Molecular function Cellular component Biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 2: 42.44 – 42.49 Mb Chr 17: 83.89 – 83.94 Mb PubMed search[3] [4] Wikidata
Potassium voltage-gated channel subfamily G member 3 is a protein that in humans is encoded by the KCNG3 gene .[5] [6] protein encoded by this gene is a voltage-gated potassium channel subunit.[6]
References [ ]
^ a b c GRCh38: Ensembl release 89: ENSG00000171126 - Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000045053 - Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Sano Y, Mochizuki S, Miyake A, Kitada C, Inamura K, Yokoi H, Nozawa K, Matsushime H, Furuichi K (Feb 2002). "Molecular cloning and characterization of Kv6.3, a novel modulatory subunit for voltage-gated K(+) channel Kv2.1". FEBS Lett . 512 (1–3): 230–4. doi :10.1016/S0014-5793(02)02267-6 . PMID 11852086 . S2CID 83987133 . ^ a b Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev . 57 (4): 473–508. doi :10.1124/pr.57.4.10 . PMID 16382104 . S2CID 219195192 .
Further reading [ ]
Mederos Y, Schnitzler M, Rinné S, Skrobek L, et al. (2009). "Mutation of histidine 105 in the T1 domain of the potassium channel Kv2.1 disrupts heteromerization with Kv6.3 and Kv6.4" . J. Biol. Chem . 284 (7): 4695–704. doi :10.1074/jbc.M808786200 PMID 19074135 . Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Ottschytsch N, Raes A, Van Hoorick D, Snyders DJ (2002). "Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome" . Proc. Natl. Acad. Sci. U.S.A . 99 (12): 7986–91. Bibcode :2002PNAS...99.7986O . doi :10.1073/pnas.122617999 PMC 123007 PMID 12060745 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Vega-Saenz de Miera EC (2004). "Modification of Kv2.1 K+ currents by the silent Kv10 subunits". Brain Res. Mol. Brain Res . 123 (1–2): 91–103. doi :10.1016/j.molbrainres.2004.01.004 . PMID 15046870 .
External links [ ]
Ligand-gated Voltage-gated
α2 δ-subunits
β-subunits
γ-subunits
Na+ : Sodium channel
Constitutively active
Epithelial sodium channel
Proton -gated
Amiloride-sensitive cation channel
Voltage-gated
Nav α
1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 7A Nav β
K+ : Potassium channel
Calcium-activated Inward-rectifier Tandem pore domain Voltage-gated
Miscellaneous
Cl− :Chloride channel
Calcium-activated chloride channels
Anoctamin
Bestrophin
Chloride Channel Accessory
CFTR CLCN
CLIC
CLNS
H+ :Proton channel M+ :CNG cation channel M+ :TRP cation channel H2 O (+ solutes ):Porin Cytoplasm :Gap junction
see also disorders
Categories :
Genes on human chromosome 2 Ion channels Membrane protein stubs
