Motilin receptor is a G protein-coupled receptor that binds motilin.[3][4] Motilin in turn is an intestinal peptide that stimulates contraction of gut smooth muscle.
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Depoortere I (2001). "Motilin and motilin receptors: characterization and functional significance". Verh. K. Acad. Geneeskd. Belg. 63 (6): 511–29. PMID11813507.
^Yang X, Dong L, Yang H (2006). "[Evidence for the presence of motilin receptor and a study on the mechanism of motilin induced Ca2+ signaling in rat myenteric neurons]". Sichuan da Xue Xue Bao Yi Xue Ban (in Chinese). 37 (5): 683–6. PMID17037727.
Further reading[]
Smith RG, Leonard R, Bailey AR, et al. (2001). "Growth hormone secretagogue receptor family members and ligands". Endocrine. 14 (1): 9–14. doi:10.1385/ENDO:14:1:009. PMID11322507. S2CID31807893.
McKee KK, Tan CP, Palyha OC, et al. (1998). "Cloning and characterization of two human G protein-coupled receptor genes (GPR38 and GPR39) related to the growth hormone secretagogue and neurotensin receptors". Genomics. 46 (3): 426–34. doi:10.1006/geno.1997.5069. PMID9441746.
Feighner SD, Tan CP, McKee KK, et al. (1999). "Receptor for motilin identified in the human gastrointestinal system". Science. 284 (5423): 2184–8. doi:10.1126/science.284.5423.2184. PMID10381885.
Miller P, Roy A, St-Pierre S, et al. (2000). "Motilin receptors in the human antrum". Am. J. Physiol. Gastrointest. Liver Physiol. 278 (1): G18–23. doi:10.1152/ajpgi.2000.278.1.G18. PMID10644557.
Thielemans L, Depoortere I, Van Assche G, et al. (2001). "Demonstration of a functional motilin receptor in TE671 cells from human cerebellum". Brain Res. 895 (1–2): 119–28. doi:10.1016/S0006-8993(01)02055-8. PMID11259768. S2CID19864565.
Thielemans L, Depoortere I, Vanden Broeck J, Peeters TL (2002). "The motilin pharmacophore in CHO cells expressing the human motilin receptor". Biochem. Biophys. Res. Commun. 293 (4): 1223–7. doi:10.1016/S0006-291X(02)00356-X. PMID12054506.
Depoortere I, Thijs T, Thielemans L, et al. (2003). "Interaction of the growth hormone-releasing peptides ghrelin and growth hormone-releasing peptide-6 with the motilin receptor in the rabbit gastric antrum". J. Pharmacol. Exp. Ther. 305 (2): 660–7. doi:10.1124/jpet.102.047563. PMID12606621. S2CID2078474.