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The cysteinyl leukotriene receptors (CysLTRs) include the following two receptors:
- Cysteinyl leukotriene receptor 1 (CysLTR1)
- Cysteinyl leukotriene receptor 2 (CysLTR2)
The recently elucidated CysLTE, represented by GPR99/OXGR1, may constitute a third CysLTR.[1]
See also[]
References[]
Cell surface receptor: G protein-coupled receptors |
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Neurotransmitter | Adrenergic |
- α1 (A
- B
- D)
- α2 (A
- B
- C)
- β1
- β2
- β3
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Purinergic |
- Adenosine (A1
- A2A
- A2B
- A3)
- P2Y (1
- 2
- 4
- 5
- 6
- 8
- 9
- 10
- 11
- 12
- 13
- 14)
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Serotonin | |
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Other |
- Acetylcholine (M1
- M2
- M3
- M4
- M5)
- Dopamine
- GHB receptor
- Histamine
- Melatonin (1A
- 1B
- 1C)
- TAAR (1
- 2
- 5
- 6
- 8
- 9)
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Metabolites and signaling molecules | Eicosanoid |
- CysLT (1
- 2)
- LTB4
- FPRL1
- OXE
- Prostaglandin
- DP (1
- 2), EP (1
- 2
- 3
- 4), FP
- Prostacyclin
- Thromboxane
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Other | |
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Peptide | |
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Miscellaneous | |
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Taste, sweet | |
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Other |
- Calcium-sensing receptor
- GABAB (1
- 2)
- Glutamate receptor (Metabotropic glutamate (1
- 2
- 3
- 4
- 5
- 6
- 7
- 8))
- GPRC6A
- GPR (156
- 158
- 179)
- RAIG (1
- 2
- 3
- 4)
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Receptor (ligands) | BLT | BLT1 |
- Agonists: 12-HETE
- Leukotriene B4
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BLT2 |
- Agonists: 12-HETE
- 12-HHT
- 15-HETE
- Leukotriene B4
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CysLT | CysLT1 |
- Agonists: Leukotriene C4
- Leukotriene D4
- Leukotriene E4
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CysLT2 |
- Agonists: Leukotriene C4
- Leukotriene D4
- Leukotriene E4
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CysLTE | |
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Enzyme (inhibitors) | 5-LOX |
- FLAP inhibitors:
- AM-679
- MK-886
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12-LOX | |
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15-LOX | |
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LTA4H |
- Captopril
- Fosinoprilat
- Ubenimex (bestatin)
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LTB4H | |
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LTC4S | |
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LTC4H | |
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LTD4 | |
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Others |
- Precursors: Linoleic acid
- γ-Linolenic acid (gamolenic acid)
- Dihomo-γ-linolenic acid
- Diacylglycerol
- Arachidonic acid
- 5-HPETE (arachidonic acid 5-hydroperoxide)
- Leukotriene A4
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- See also
- Receptor/signaling modulators
- Prostanoid signaling modulators
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Categories:
- G protein-coupled receptors
- Transmembrane receptor stubs