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KCNH8 Identifiers Aliases KCNH8 , ELK, ELK1, Kv12.1, elk3, potassium voltage-gated channel subfamily H member 8External IDs OMIM : 608260 MGI : 2445160 HomoloGene : 14332 GeneCards : KCNH8 Gene location (Human ) Chr. Chromosome 3 (human) [1] Band 3p24.3 Start 19,148,510 bp [1] End 19,535,642 bp [1]
Gene location (Mouse ) Chr. Chromosome 17 (mouse)[2] Band 17|17 C Start 52,602,709 bp [2] End 52,979,194 bp [2]
Gene ontology Molecular function Cellular component Biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 3: 19.15 – 19.54 Mb Chr 17: 52.6 – 52.98 Mb PubMed search[3] [4] Wikidata
Potassium voltage-gated channel subfamily H member 8 is a protein that in humans is encoded by the KCNH8 gene .[5] The protein encoded by this gene is a voltage-gated potassium channel subunit.[5]
References [ ]
^ a b c GRCh38: Ensembl release 89: ENSG00000183960 - Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000035580 - Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ a b Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev . 57 (4): 473–508. doi :10.1124/pr.57.4.10 . PMID 16382104 . S2CID 219195192 .
Further reading [ ]
Baxter DF, Kirk M, Garcia AF, et al. (2002). "A novel membrane potential-sensitive fluorescent dye improves cell-based assays for ion channels" . Journal of Biomolecular Screening . 7 (1): 79–85. doi :10.1089/108705702753520369 . PMID 11897058 .
Kiel DP, Demissie S, Dupuis J , et al. (2007). "Genome-wide association with bone mass and geometry in the Framingham Heart Study" . BMC Med. Genet . 8 Suppl 1: S14. doi :10.1186/1471-2350-8-S1-S14 . PMC 1995606 . PMID 17903296 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
Zou A, Lin Z, Humble M, et al. (2003). "Distribution and functional properties of human KCNH8 (Elk1) potassium channels". Am. J. Physiol., Cell Physiol . 285 (6): C1356–66. CiteSeerX 10.1.1.196.6556 . doi :10.1152/ajpcell.00179.2003 . PMID 12890647 .
External links [ ]
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Na+ : Sodium channel
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K+ : Potassium channel
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Cl− : Chloride channel
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H+ : Proton channel M+ : CNG cation channel M+ : TRP cation channel H2 O (+ solutes ): Porin Cytoplasm : Gap junction
see also disorders
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